Advances in the diagnosis and management of chronic pulmonary aspiration in children

R. Paul Boesch, Cori L Daines, J. P. Willging, A. Kaul, A. P. Cohen, R. E. Wood, R. S. Amin

Research output: Contribution to journalArticle

106 Citations (Scopus)

Abstract

Chronic pulmonary aspiration (CPA) in children is an important cause of recurrent pneumonia, progressive lung injury, respiratory disability and death. It is sporadic, intermittent and variable, and often occurs in children with complicated underlying medical conditions and syndromes that produce symptoms indistinguishable from CPA. For most types of aspiration there is no gold-standard diagnostic test. The diagnosis of CPA is currently made clinically with some supporting diagnostic evaluations, but often not until significant lung injury has been sustained. Despite multiple diagnostic techniques, the diagnosis or exclusion of CPA in children is challenging. This is of particular concern given the outcome of unrecognised progressive lung injury and the invasiveness of definitive therapies. Although new techniques have been introduced since the 1990s and significant advances in the understanding of dysphagia and gastro-oesophageal reflux have been made, characterisation of the aspirating child remains elusive.

Original languageEnglish (US)
Pages (from-to)847-861
Number of pages15
JournalEuropean Respiratory Journal
Volume28
Issue number4
DOIs
StatePublished - Oct 2006
Externally publishedYes

Fingerprint

Lung Injury
Lung
Deglutition Disorders
Gastroesophageal Reflux
Routine Diagnostic Tests
Gold
Pneumonia
Therapeutics

Keywords

  • Aspiration
  • Bronchoscopy
  • Children
  • Fibreoptic-endoscopic evaluation of swallowing
  • Oesophageal impedance

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Advances in the diagnosis and management of chronic pulmonary aspiration in children. / Boesch, R. Paul; Daines, Cori L; Willging, J. P.; Kaul, A.; Cohen, A. P.; Wood, R. E.; Amin, R. S.

In: European Respiratory Journal, Vol. 28, No. 4, 10.2006, p. 847-861.

Research output: Contribution to journalArticle

Boesch, R. Paul ; Daines, Cori L ; Willging, J. P. ; Kaul, A. ; Cohen, A. P. ; Wood, R. E. ; Amin, R. S. / Advances in the diagnosis and management of chronic pulmonary aspiration in children. In: European Respiratory Journal. 2006 ; Vol. 28, No. 4. pp. 847-861.
@article{a9ab0880d914426281a35998b61994df,
title = "Advances in the diagnosis and management of chronic pulmonary aspiration in children",
abstract = "Chronic pulmonary aspiration (CPA) in children is an important cause of recurrent pneumonia, progressive lung injury, respiratory disability and death. It is sporadic, intermittent and variable, and often occurs in children with complicated underlying medical conditions and syndromes that produce symptoms indistinguishable from CPA. For most types of aspiration there is no gold-standard diagnostic test. The diagnosis of CPA is currently made clinically with some supporting diagnostic evaluations, but often not until significant lung injury has been sustained. Despite multiple diagnostic techniques, the diagnosis or exclusion of CPA in children is challenging. This is of particular concern given the outcome of unrecognised progressive lung injury and the invasiveness of definitive therapies. Although new techniques have been introduced since the 1990s and significant advances in the understanding of dysphagia and gastro-oesophageal reflux have been made, characterisation of the aspirating child remains elusive.",
keywords = "Aspiration, Bronchoscopy, Children, Fibreoptic-endoscopic evaluation of swallowing, Oesophageal impedance",
author = "Boesch, {R. Paul} and Daines, {Cori L} and Willging, {J. P.} and A. Kaul and Cohen, {A. P.} and Wood, {R. E.} and Amin, {R. S.}",
year = "2006",
month = "10",
doi = "10.1183/09031936.06.00138305",
language = "English (US)",
volume = "28",
pages = "847--861",
journal = "European Respiratory Journal",
issn = "0903-1936",
publisher = "European Respiratory Society",
number = "4",

}

TY - JOUR

T1 - Advances in the diagnosis and management of chronic pulmonary aspiration in children

AU - Boesch, R. Paul

AU - Daines, Cori L

AU - Willging, J. P.

AU - Kaul, A.

AU - Cohen, A. P.

AU - Wood, R. E.

AU - Amin, R. S.

PY - 2006/10

Y1 - 2006/10

N2 - Chronic pulmonary aspiration (CPA) in children is an important cause of recurrent pneumonia, progressive lung injury, respiratory disability and death. It is sporadic, intermittent and variable, and often occurs in children with complicated underlying medical conditions and syndromes that produce symptoms indistinguishable from CPA. For most types of aspiration there is no gold-standard diagnostic test. The diagnosis of CPA is currently made clinically with some supporting diagnostic evaluations, but often not until significant lung injury has been sustained. Despite multiple diagnostic techniques, the diagnosis or exclusion of CPA in children is challenging. This is of particular concern given the outcome of unrecognised progressive lung injury and the invasiveness of definitive therapies. Although new techniques have been introduced since the 1990s and significant advances in the understanding of dysphagia and gastro-oesophageal reflux have been made, characterisation of the aspirating child remains elusive.

AB - Chronic pulmonary aspiration (CPA) in children is an important cause of recurrent pneumonia, progressive lung injury, respiratory disability and death. It is sporadic, intermittent and variable, and often occurs in children with complicated underlying medical conditions and syndromes that produce symptoms indistinguishable from CPA. For most types of aspiration there is no gold-standard diagnostic test. The diagnosis of CPA is currently made clinically with some supporting diagnostic evaluations, but often not until significant lung injury has been sustained. Despite multiple diagnostic techniques, the diagnosis or exclusion of CPA in children is challenging. This is of particular concern given the outcome of unrecognised progressive lung injury and the invasiveness of definitive therapies. Although new techniques have been introduced since the 1990s and significant advances in the understanding of dysphagia and gastro-oesophageal reflux have been made, characterisation of the aspirating child remains elusive.

KW - Aspiration

KW - Bronchoscopy

KW - Children

KW - Fibreoptic-endoscopic evaluation of swallowing

KW - Oesophageal impedance

UR - http://www.scopus.com/inward/record.url?scp=33847341624&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33847341624&partnerID=8YFLogxK

U2 - 10.1183/09031936.06.00138305

DO - 10.1183/09031936.06.00138305

M3 - Article

C2 - 17012631

AN - SCOPUS:33847341624

VL - 28

SP - 847

EP - 861

JO - European Respiratory Journal

JF - European Respiratory Journal

SN - 0903-1936

IS - 4

ER -