AIDS-Kaposi's sarcoma complex

Evolution of a full-blown lymphologic syndrome

Marlys H Witte, C. L. Witte

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A hypothesis is presented to explain the link between acquired immunodeficiency syndrome (AIDS) and Kaposi's sarcoma (KS). According to this hypothesis, AIDS involves all four components of the integrated lymphatic system-lymphatics, lymph nodes, lymphocytes, and lymph- and thereby resembles various congenital and acquired lymphologic syndromes characterized by one or more of the following features: lymphostasis, angiogenesis, and fibrosis; depletion of immunocompetent cells and immunosuppression; opportunistic infections; and vascular neoplasms. A better understanding of the steps in the evolution of these processes and their interrelationships to the four components of the lymphatic system should provide insight into the immunopathogenesis of AIDS-KS as well as its detection and treatment.

Original languageEnglish (US)
Pages (from-to)4-10
Number of pages7
JournalLymphology
Volume21
Issue number1
StatePublished - 1988

Fingerprint

Kaposi's Sarcoma
Lymphatic System
Acquired Immunodeficiency Syndrome
Vascular Neoplasms
Opportunistic Infections
Lymph
Immunosuppression
Fibrosis
Lymph Nodes
Lymphocytes
Therapeutics

ASJC Scopus subject areas

  • Immunology

Cite this

AIDS-Kaposi's sarcoma complex : Evolution of a full-blown lymphologic syndrome. / Witte, Marlys H; Witte, C. L.

In: Lymphology, Vol. 21, No. 1, 1988, p. 4-10.

Research output: Contribution to journalArticle

@article{fc6a0ebcd24e4a4ebb4f1f1672aac31f,
title = "AIDS-Kaposi's sarcoma complex: Evolution of a full-blown lymphologic syndrome",
abstract = "A hypothesis is presented to explain the link between acquired immunodeficiency syndrome (AIDS) and Kaposi's sarcoma (KS). According to this hypothesis, AIDS involves all four components of the integrated lymphatic system-lymphatics, lymph nodes, lymphocytes, and lymph- and thereby resembles various congenital and acquired lymphologic syndromes characterized by one or more of the following features: lymphostasis, angiogenesis, and fibrosis; depletion of immunocompetent cells and immunosuppression; opportunistic infections; and vascular neoplasms. A better understanding of the steps in the evolution of these processes and their interrelationships to the four components of the lymphatic system should provide insight into the immunopathogenesis of AIDS-KS as well as its detection and treatment.",
author = "Witte, {Marlys H} and Witte, {C. L.}",
year = "1988",
language = "English (US)",
volume = "21",
pages = "4--10",
journal = "Lymphology",
issn = "0024-7766",
publisher = "International Society of Lymphology",
number = "1",

}

TY - JOUR

T1 - AIDS-Kaposi's sarcoma complex

T2 - Evolution of a full-blown lymphologic syndrome

AU - Witte, Marlys H

AU - Witte, C. L.

PY - 1988

Y1 - 1988

N2 - A hypothesis is presented to explain the link between acquired immunodeficiency syndrome (AIDS) and Kaposi's sarcoma (KS). According to this hypothesis, AIDS involves all four components of the integrated lymphatic system-lymphatics, lymph nodes, lymphocytes, and lymph- and thereby resembles various congenital and acquired lymphologic syndromes characterized by one or more of the following features: lymphostasis, angiogenesis, and fibrosis; depletion of immunocompetent cells and immunosuppression; opportunistic infections; and vascular neoplasms. A better understanding of the steps in the evolution of these processes and their interrelationships to the four components of the lymphatic system should provide insight into the immunopathogenesis of AIDS-KS as well as its detection and treatment.

AB - A hypothesis is presented to explain the link between acquired immunodeficiency syndrome (AIDS) and Kaposi's sarcoma (KS). According to this hypothesis, AIDS involves all four components of the integrated lymphatic system-lymphatics, lymph nodes, lymphocytes, and lymph- and thereby resembles various congenital and acquired lymphologic syndromes characterized by one or more of the following features: lymphostasis, angiogenesis, and fibrosis; depletion of immunocompetent cells and immunosuppression; opportunistic infections; and vascular neoplasms. A better understanding of the steps in the evolution of these processes and their interrelationships to the four components of the lymphatic system should provide insight into the immunopathogenesis of AIDS-KS as well as its detection and treatment.

UR - http://www.scopus.com/inward/record.url?scp=0023947657&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023947657&partnerID=8YFLogxK

M3 - Article

VL - 21

SP - 4

EP - 10

JO - Lymphology

JF - Lymphology

SN - 0024-7766

IS - 1

ER -