American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer

Debbie Saslow, Diane Solomon, Herschel W. Lawson, Maureen Killackey, Shalini L. Kulasingam, Joanna Cain, Francisco A.R. Garcia, Ann T. Moriarty, Alan G. Waxman, David C. Wilbur, Nicolas Wentzensen, Levi S. Downs, Mark Spitzer, Anna Barbara Moscicki, Eduardo L. Franco, Mark H. Stoler, Mark Schiffman, Philip E. Castle, Evan R. Myers

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Abstract

An update to the American Cancer Society (ACS) guideline regarding screening for the early detection of cervical precancerous lesions and cancer is presented. The guidelines are based on a systematic evidence review, contributions from 6 working groups, and a recent symposium cosponsored by the ACS, the American Society for Colposcopy and Cervical Pathology, and the American Society for Clinical Pathology, which was attended by 25 organizations. The new screening recommendations address age-appropriate screening strategies, including the use of cytology and high-risk human papillomavirus (HPV) testing, follow-up (eg, the management of screen positives and screening intervals for screen negatives) of women after screening, the age at which to exit screening, future considerations regarding HPV testing alone as a primary screening approach, and screening strategies for women vaccinated against HPV16 and HPV18 infections. Cervical cancer screening has successfully decreased cervical cancer incidence and mortality. The American Cancer Society (ACS) guideline for the early detection of cervical cancer was last reviewed and updated in 2002; for the first time, those recommendations incorporated human papillomavirus (HPV) DNA testing.1 Since that time, numerous studies have been published that support changes to recommended age-appropriate screening as well as the management of abnormal screening results, as summarized in Table 1. Copyright

Original languageEnglish (US)
Pages (from-to)516-542
Number of pages27
JournalAmerican journal of clinical pathology
Volume137
Issue number4
DOIs
StatePublished - Apr 1 2012

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ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Saslow, D., Solomon, D., Lawson, H. W., Killackey, M., Kulasingam, S. L., Cain, J., Garcia, F. A. R., Moriarty, A. T., Waxman, A. G., Wilbur, D. C., Wentzensen, N., Downs, L. S., Spitzer, M., Moscicki, A. B., Franco, E. L., Stoler, M. H., Schiffman, M., Castle, P. E., & Myers, E. R. (2012). American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer. American journal of clinical pathology, 137(4), 516-542. https://doi.org/10.1309/AJCPTGD94EVRSJCG