Amphotercin B Lipid Complex Treatment of a Leukemic Child wlth Disseminated Fusarrium solani Infection

Thomas S. Patterson, Leslie L. Barton, Ziad M. Shehab, John J. Hutter

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

We report a case of Fusarium solani infection in a 2'2-year-old girl with acute lymphoblastic leukemia and severe neutropenia. The infection, initially limited to her sinuses, became disseminated, as evidenced by the development of a characteristic cutaneous lesion on her left leg after a cumulative dose of amphotericin B of 18.3 mg/kg. Amphotericin B lipid complex (ABLC), 5 mg/kg/day, in conjunction with repeated surgical debridement of the sinuses and correction of neutropenia with granulocyte colony stimulating factor (GCSF), led to clinical and mycologic cure.

Original languageEnglish (US)
Pages (from-to)257-260
Number of pages4
JournalClinical Pediatrics
Volume35
Issue number5
DOIs
StatePublished - May 1996

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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