An AC electroosmotic processor for biomolecules

Pak Kin Wong, Che Yang Chen, Tza Huei Wang, Chih Ming Ho

Research output: Chapter in Book/Report/Conference proceedingConference contribution

22 Scopus citations

Abstract

This paper describes an AC electrokinetic processor for biomedical analysis systems. The processor exploits AC electroosmosis for concentrating bioparticles, such as cells and molecules. Particle image velocimetry (PIV) is used to characterize the AC electroosmotic flow. A combination of the AC electroosmotic flow and other electrokinetic forces allows collection and concentration of the bioparticles. By optimizing the operating parameters, we have successfully demonstrated concentration of various biological objects, such as E. coli bacteria, λ phage DNA, and single-strand DNA fragments as small as 20 bases.

Original languageEnglish (US)
Title of host publicationTRANSDUCERS 2003 - 12th International Conference on Solid-State Sensors, Actuators and Microsystems, Digest of Technical Papers
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages20-23
Number of pages4
Volume1
ISBN (Print)0780377311, 9780780377318
DOIs
StatePublished - 2003
Externally publishedYes
Event12th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2003 - Digest of Technical Papers - Boston, United States
Duration: Jun 8 2003Jun 12 2003

Other

Other12th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2003 - Digest of Technical Papers
CountryUnited States
CityBoston
Period6/8/036/12/03

Keywords

  • Aerospace engineering
  • Biochemical analysis
  • Biomedical engineering
  • DNA
  • Electrodes
  • Electrokinetics
  • Fabrication
  • Microfluidics
  • Microorganisms
  • Molecular biophysics

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

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  • Cite this

    Wong, P. K., Chen, C. Y., Wang, T. H., & Ho, C. M. (2003). An AC electroosmotic processor for biomolecules. In TRANSDUCERS 2003 - 12th International Conference on Solid-State Sensors, Actuators and Microsystems, Digest of Technical Papers (Vol. 1, pp. 20-23). [1215243] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/SENSOR.2003.1215243