An Investigation of Quasi-Vertex Views in Brain SPECT Imaging-Initial Results

Justin C. Goding, Benjamin Auer, Kesava S. Kalluri, Arda Konik, Navid Zeraatkar, Timothy J. Fromme, Yulun He, George I. Zubal, Lars R Furenlid, Michael A. King

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

A next-generation, adaptive, brain-imaging, single photon emission computed tomography system is currently under development at the Universities of Arizona and Massachusetts. The proposed multi-pinhole based modular gamma camera configuration enables the acquisition of 'quasi-vertex' views i.e., views close to the vertex. This study is concerned with understanding how activity inferior to the brain will influence these views and ultimately, the reconstruction of the volume of interest. Analytical models can provide some measure of the detected primary gamma radiation originating in an organ or tissue outside the region of interest. Scattered gamma radiation will be detected as well but given the difficulty in modeling such phenomena, Monte Carlo simulations are used to quantify its effect. Using computer generated phantoms, the influence of activity from organs and tissues in the thorax, neck and lower head as compared to that from brain structures in the quasivertex views, will be detected, identified and quantified. The simulation consists of two components: detectors and sources. The detectors were simulated gamma camera modules consisting of a tungsten pinhole collimator, an air gap, and a NaI(Tl) scintillator surrounded by lead shielding. The sources were phantoms with activity (I-123, primary gamma photons at 159 keV) set in the liver, lungs, striatum, salivary glands and the thyroid.

Original languageEnglish (US)
Title of host publication2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781538622827
DOIs
StatePublished - Nov 12 2018
Event2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Atlanta, United States
Duration: Oct 21 2017Oct 28 2017

Other

Other2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017
CountryUnited States
CityAtlanta
Period10/21/1710/28/17

ASJC Scopus subject areas

  • Instrumentation
  • Radiology Nuclear Medicine and imaging
  • Nuclear and High Energy Physics

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    Goding, J. C., Auer, B., Kalluri, K. S., Konik, A., Zeraatkar, N., Fromme, T. J., He, Y., Zubal, G. I., Furenlid, L. R., & King, M. A. (2018). An Investigation of Quasi-Vertex Views in Brain SPECT Imaging-Initial Results. In 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings [8532719] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NSSMIC.2017.8532719