An MRI-driven practice: A new perspective on MRI for the evaluation of adenocarcinoma of the head of the pancreas

Elliot B. Tapper, Diego R Martin, N. Volkan Adsay, David Kooby, Bobby T Kalb, Juan M. Sarmiento

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Objectives: The purpose of the study was to describe the MRI-driven management of masses at the head of the pancreas. Main outcome measures: The main outcome measure was tumor resectability. Methods: A retrospective review of prospective radiographic diagnoses was undertaken. Results: Between 2004 and 2008, we have treated 124 patients for a radiographic diagnosis of adenocarcinoma of the head of the pancreas. This diagnosis was correct in 96.0% of the time. MRI was 100% sensitive in determining resectability, 73.2-78.9% specific, and had an overall accuracy of 86.3-87.5%. MRI could detect venous and arterial involvement with 95% and 95.9% accuracy, respectively, and missed only six metastases. Conclusion: MRI is a useful tool in the preoperative imaging of pancreatic head lesions that is highly sensitive and very specific for resectable disease. Prospective trials of MRI in this setting are indicated.

Original languageEnglish (US)
Pages (from-to)1292-1297
Number of pages6
JournalJournal of Gastrointestinal Surgery
Volume14
Issue number8
DOIs
StatePublished - 2010
Externally publishedYes

Fingerprint

Pancreas
Adenocarcinoma
Outcome Assessment (Health Care)
Neoplasm Metastasis
Neoplasms

Keywords

  • Adenocarcinoma
  • Cancer imaging
  • Head of the pancreas
  • MRI
  • Pancreas
  • Pancreatic cancer
  • Pancreaticoduodenectomy

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology
  • Medicine(all)

Cite this

An MRI-driven practice : A new perspective on MRI for the evaluation of adenocarcinoma of the head of the pancreas. / Tapper, Elliot B.; Martin, Diego R; Adsay, N. Volkan; Kooby, David; Kalb, Bobby T; Sarmiento, Juan M.

In: Journal of Gastrointestinal Surgery, Vol. 14, No. 8, 2010, p. 1292-1297.

Research output: Contribution to journalArticle

@article{97384f85049648cdbbc75749c1b54747,
title = "An MRI-driven practice: A new perspective on MRI for the evaluation of adenocarcinoma of the head of the pancreas",
abstract = "Objectives: The purpose of the study was to describe the MRI-driven management of masses at the head of the pancreas. Main outcome measures: The main outcome measure was tumor resectability. Methods: A retrospective review of prospective radiographic diagnoses was undertaken. Results: Between 2004 and 2008, we have treated 124 patients for a radiographic diagnosis of adenocarcinoma of the head of the pancreas. This diagnosis was correct in 96.0{\%} of the time. MRI was 100{\%} sensitive in determining resectability, 73.2-78.9{\%} specific, and had an overall accuracy of 86.3-87.5{\%}. MRI could detect venous and arterial involvement with 95{\%} and 95.9{\%} accuracy, respectively, and missed only six metastases. Conclusion: MRI is a useful tool in the preoperative imaging of pancreatic head lesions that is highly sensitive and very specific for resectable disease. Prospective trials of MRI in this setting are indicated.",
keywords = "Adenocarcinoma, Cancer imaging, Head of the pancreas, MRI, Pancreas, Pancreatic cancer, Pancreaticoduodenectomy",
author = "Tapper, {Elliot B.} and Martin, {Diego R} and Adsay, {N. Volkan} and David Kooby and Kalb, {Bobby T} and Sarmiento, {Juan M.}",
year = "2010",
doi = "10.1007/s11605-010-1221-z",
language = "English (US)",
volume = "14",
pages = "1292--1297",
journal = "Journal of Gastrointestinal Surgery",
issn = "1091-255X",
publisher = "Springer New York",
number = "8",

}

TY - JOUR

T1 - An MRI-driven practice

T2 - A new perspective on MRI for the evaluation of adenocarcinoma of the head of the pancreas

AU - Tapper, Elliot B.

AU - Martin, Diego R

AU - Adsay, N. Volkan

AU - Kooby, David

AU - Kalb, Bobby T

AU - Sarmiento, Juan M.

PY - 2010

Y1 - 2010

N2 - Objectives: The purpose of the study was to describe the MRI-driven management of masses at the head of the pancreas. Main outcome measures: The main outcome measure was tumor resectability. Methods: A retrospective review of prospective radiographic diagnoses was undertaken. Results: Between 2004 and 2008, we have treated 124 patients for a radiographic diagnosis of adenocarcinoma of the head of the pancreas. This diagnosis was correct in 96.0% of the time. MRI was 100% sensitive in determining resectability, 73.2-78.9% specific, and had an overall accuracy of 86.3-87.5%. MRI could detect venous and arterial involvement with 95% and 95.9% accuracy, respectively, and missed only six metastases. Conclusion: MRI is a useful tool in the preoperative imaging of pancreatic head lesions that is highly sensitive and very specific for resectable disease. Prospective trials of MRI in this setting are indicated.

AB - Objectives: The purpose of the study was to describe the MRI-driven management of masses at the head of the pancreas. Main outcome measures: The main outcome measure was tumor resectability. Methods: A retrospective review of prospective radiographic diagnoses was undertaken. Results: Between 2004 and 2008, we have treated 124 patients for a radiographic diagnosis of adenocarcinoma of the head of the pancreas. This diagnosis was correct in 96.0% of the time. MRI was 100% sensitive in determining resectability, 73.2-78.9% specific, and had an overall accuracy of 86.3-87.5%. MRI could detect venous and arterial involvement with 95% and 95.9% accuracy, respectively, and missed only six metastases. Conclusion: MRI is a useful tool in the preoperative imaging of pancreatic head lesions that is highly sensitive and very specific for resectable disease. Prospective trials of MRI in this setting are indicated.

KW - Adenocarcinoma

KW - Cancer imaging

KW - Head of the pancreas

KW - MRI

KW - Pancreas

KW - Pancreatic cancer

KW - Pancreaticoduodenectomy

UR - http://www.scopus.com/inward/record.url?scp=77954957704&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77954957704&partnerID=8YFLogxK

U2 - 10.1007/s11605-010-1221-z

DO - 10.1007/s11605-010-1221-z

M3 - Article

C2 - 20467829

AN - SCOPUS:77954957704

VL - 14

SP - 1292

EP - 1297

JO - Journal of Gastrointestinal Surgery

JF - Journal of Gastrointestinal Surgery

SN - 1091-255X

IS - 8

ER -