Analysis of haloacetic acids, bromate, and dalapon in natural waters by ion chromatography–tandem mass spectrometry

Shimin Wu, Tarun Anumol, Jay Gandhi, Shane A. Snyder

Research output: Research - peer-reviewArticle

Abstract

The addition of oxidants for disinfecting water can lead to the formation of potentially carcinogenic compounds referred to as disinfection byproducts (DBPs). Haloacetic acids (HAAs) are one of the most widely detected DBPs in US water utilities and some of them are regulated by the US Environmental Protection Agency (USEPA). The present study developed a method to analyze all the compounds in the USEPA method 557 (nine HAAs, bromate and dalapon) plus four potentially more toxic iodinated HAAs in water by coupling ion chromatography with tandem mass spectrometry (IC–MS/MS). This aqueous direct injection method has significant advantages over traditional GC methods, which require a derivatization and sample extraction that are laborious, time-consuming, and can negatively impact reproducibility. The method developed in this study requires half the time of the current USEPA method 557 on IC–MS/MS while including more compounds and achieving sub-μg/L level method detection limits (MDLs) for all 15 target analytes. The single laboratory lowest concentration minimum reporting level (LCMRL) has also been determined in reagent water, which ranged from 0.011 to 0.62 μg/L for the analytes. The mean recoveries of the analytes during matrix spike recovery tests were 77–125% in finished drinking water and 81–112% in surface water. This method was then applied to untreated, chlorinated, and chloraminated groundwater and surface water samples. Bromate and 9 HAAs were detected at different levels in some of these samples.

LanguageEnglish (US)
Pages100-107
Number of pages8
JournalJournal of Chromatography A
Volume1487
DOIs
StatePublished - Mar 3 2017

Fingerprint

Bromates
Ion chromatography
Mass spectrometry
Acids
Water
dalapon
Tandem Mass Spectrometry
Chromatography
Ions
Environmental Protection Agency
Surface waters
Byproducts
Recovery
United States Environmental Protection Agency
Poisons
Direct injection
Oxidants
Drinking Water
Groundwater
Disinfection

Keywords

  • Bromate
  • Dalapon
  • Haloacetic acids
  • Ion-chromatography
  • Tandem mass spectrometry

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

Cite this

Analysis of haloacetic acids, bromate, and dalapon in natural waters by ion chromatography–tandem mass spectrometry. / Wu, Shimin; Anumol, Tarun; Gandhi, Jay; Snyder, Shane A.

In: Journal of Chromatography A, Vol. 1487, 03.03.2017, p. 100-107.

Research output: Research - peer-reviewArticle

@article{2e6df2c92c89410ca7869d60db60610c,
title = "Analysis of haloacetic acids, bromate, and dalapon in natural waters by ion chromatography–tandem mass spectrometry",
abstract = "The addition of oxidants for disinfecting water can lead to the formation of potentially carcinogenic compounds referred to as disinfection byproducts (DBPs). Haloacetic acids (HAAs) are one of the most widely detected DBPs in US water utilities and some of them are regulated by the US Environmental Protection Agency (USEPA). The present study developed a method to analyze all the compounds in the USEPA method 557 (nine HAAs, bromate and dalapon) plus four potentially more toxic iodinated HAAs in water by coupling ion chromatography with tandem mass spectrometry (IC–MS/MS). This aqueous direct injection method has significant advantages over traditional GC methods, which require a derivatization and sample extraction that are laborious, time-consuming, and can negatively impact reproducibility. The method developed in this study requires half the time of the current USEPA method 557 on IC–MS/MS while including more compounds and achieving sub-μg/L level method detection limits (MDLs) for all 15 target analytes. The single laboratory lowest concentration minimum reporting level (LCMRL) has also been determined in reagent water, which ranged from 0.011 to 0.62 μg/L for the analytes. The mean recoveries of the analytes during matrix spike recovery tests were 77–125% in finished drinking water and 81–112% in surface water. This method was then applied to untreated, chlorinated, and chloraminated groundwater and surface water samples. Bromate and 9 HAAs were detected at different levels in some of these samples.",
keywords = "Bromate, Dalapon, Haloacetic acids, Ion-chromatography, Tandem mass spectrometry",
author = "Shimin Wu and Tarun Anumol and Jay Gandhi and Snyder, {Shane A.}",
year = "2017",
month = "3",
doi = "10.1016/j.chroma.2017.01.006",
volume = "1487",
pages = "100--107",
journal = "Journal of Chromatography A",
issn = "0021-9673",

}

TY - JOUR

T1 - Analysis of haloacetic acids, bromate, and dalapon in natural waters by ion chromatography–tandem mass spectrometry

AU - Wu,Shimin

AU - Anumol,Tarun

AU - Gandhi,Jay

AU - Snyder,Shane A.

PY - 2017/3/3

Y1 - 2017/3/3

N2 - The addition of oxidants for disinfecting water can lead to the formation of potentially carcinogenic compounds referred to as disinfection byproducts (DBPs). Haloacetic acids (HAAs) are one of the most widely detected DBPs in US water utilities and some of them are regulated by the US Environmental Protection Agency (USEPA). The present study developed a method to analyze all the compounds in the USEPA method 557 (nine HAAs, bromate and dalapon) plus four potentially more toxic iodinated HAAs in water by coupling ion chromatography with tandem mass spectrometry (IC–MS/MS). This aqueous direct injection method has significant advantages over traditional GC methods, which require a derivatization and sample extraction that are laborious, time-consuming, and can negatively impact reproducibility. The method developed in this study requires half the time of the current USEPA method 557 on IC–MS/MS while including more compounds and achieving sub-μg/L level method detection limits (MDLs) for all 15 target analytes. The single laboratory lowest concentration minimum reporting level (LCMRL) has also been determined in reagent water, which ranged from 0.011 to 0.62 μg/L for the analytes. The mean recoveries of the analytes during matrix spike recovery tests were 77–125% in finished drinking water and 81–112% in surface water. This method was then applied to untreated, chlorinated, and chloraminated groundwater and surface water samples. Bromate and 9 HAAs were detected at different levels in some of these samples.

AB - The addition of oxidants for disinfecting water can lead to the formation of potentially carcinogenic compounds referred to as disinfection byproducts (DBPs). Haloacetic acids (HAAs) are one of the most widely detected DBPs in US water utilities and some of them are regulated by the US Environmental Protection Agency (USEPA). The present study developed a method to analyze all the compounds in the USEPA method 557 (nine HAAs, bromate and dalapon) plus four potentially more toxic iodinated HAAs in water by coupling ion chromatography with tandem mass spectrometry (IC–MS/MS). This aqueous direct injection method has significant advantages over traditional GC methods, which require a derivatization and sample extraction that are laborious, time-consuming, and can negatively impact reproducibility. The method developed in this study requires half the time of the current USEPA method 557 on IC–MS/MS while including more compounds and achieving sub-μg/L level method detection limits (MDLs) for all 15 target analytes. The single laboratory lowest concentration minimum reporting level (LCMRL) has also been determined in reagent water, which ranged from 0.011 to 0.62 μg/L for the analytes. The mean recoveries of the analytes during matrix spike recovery tests were 77–125% in finished drinking water and 81–112% in surface water. This method was then applied to untreated, chlorinated, and chloraminated groundwater and surface water samples. Bromate and 9 HAAs were detected at different levels in some of these samples.

KW - Bromate

KW - Dalapon

KW - Haloacetic acids

KW - Ion-chromatography

KW - Tandem mass spectrometry

UR - http://www.scopus.com/inward/record.url?scp=85010006275&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85010006275&partnerID=8YFLogxK

U2 - 10.1016/j.chroma.2017.01.006

DO - 10.1016/j.chroma.2017.01.006

M3 - Article

VL - 1487

SP - 100

EP - 107

JO - Journal of Chromatography A

T2 - Journal of Chromatography A

JF - Journal of Chromatography A

SN - 0021-9673

ER -