Androgen Action and Stress

M. A. Holschbach, Robert J Handa

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Androgens belong to a class of steroid hormones that circulate at high levels in males. However, androgens should not be thought of as exclusively male hormones since they are also produced in females, though at much lower levels. The predominant mode of androgen action is through binding in target tissues to a specific receptor termed the androgen receptor. This receptor can regulate the expression of a set of androgen-responsive genes. The synthesis, transport, and release of androgens to the bloodstream, their actions on target tissues, and their effects on stressor related neuroendocrine function and behaviors are addressed here.

Original languageEnglish (US)
Title of host publicationHandbook of Stress Series
PublisherElsevier Inc.
Pages227-235
Number of pages9
Volume2
ISBN (Electronic)9780128024232
ISBN (Print)9780128021750
DOIs
StatePublished - Jan 13 2017
Externally publishedYes

Keywords

  • Androgen receptor
  • Glucocorticoid
  • Neuroendocrinology
  • Steroid
  • Testosterone

ASJC Scopus subject areas

  • Neuroscience(all)

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  • Cite this

    Holschbach, M. A., & Handa, R. J. (2017). Androgen Action and Stress. In Handbook of Stress Series (Vol. 2, pp. 227-235). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-802175-0.00022-X