Antimicrobial resistance in Bacteroides spp.

Occurrence and dissemination

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Bacteroides spp. organisms, though important human commensals, are also opportunistic pathogens when they escape the colonic milieu. Resistance to multiple antibiotics has been increasing in Bacteroides spp. for decades, and is primarily due to horizontal gene transfer of a plethora of mobile elements. The mechanistic aspects of conjugation in Bacteroides spp. are only now being elucidated at a functional level. There appear to be key differences between Bacteroides spp. and non-Bacteroides spp. conjugation systems that may contribute to promiscuous gene transfer within and from this genus. This review summarizes the mechanisms of action and resistance of antibiotics used to treat Bacteroides spp. infections, and highlights current information on conjugation-based DNA exchange.

Original languageEnglish (US)
Pages (from-to)413-423
Number of pages11
JournalFuture Microbiology
Volume4
Issue number4
DOIs
StatePublished - 2009
Externally publishedYes

Fingerprint

Bacteroides
Horizontal Gene Transfer
Microbial Drug Resistance
Anti-Bacterial Agents
DNA
Infection
Genes

Keywords

  • Anaerobe
  • Antibiotic resistance
  • Bacteroides
  • Conjugation
  • Horizontal gene transfer
  • Mating apparatus
  • Opportunistic pathogen
  • Relaxosome

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

Cite this

Antimicrobial resistance in Bacteroides spp. Occurrence and dissemination. / Vedantam, Gayatri.

In: Future Microbiology, Vol. 4, No. 4, 2009, p. 413-423.

Research output: Contribution to journalArticle

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