Antioxidants and AIDS

Zhen Zhang, Paula Inserra, Bailin Liang, Ronald R Watson

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Acquired immunodeficiency syndrome (AIDS) is a result of infection with human immunodeficiency virus (HIV-1 or HIV-2) which eventually destroys subset CD4+ helper T lymphocytes. This results in enhanced susceptibility to opportunistic infection and neoplasms. Oxidative stress plays a major role in the progression of HIV infection to AIDS and has been suggested to contribute to the decline in CD4+ lymphocytes. The existence of oxidative stress in HIV infection and AIDS is exemplified by the excess production of reactive oxygen species (ROS) and a general loss of antioxidant defenses in HIV-infected patients. Therefore, the reduction of oxidative stress by antioxidant treatment may be a desirable therapy during the asymptotic HIV infection as well as advanced AIDS.

Original languageEnglish (US)
Title of host publicationNutrients and Foods in Aids
PublisherCRC Press
Pages179-192
Number of pages14
ISBN (Electronic)9781351427432
ISBN (Print)084938561X, 9780849385612
DOIs
StatePublished - Jan 1 2017

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Acquired Immunodeficiency Syndrome
Antioxidants
HIV Infections
Oxidative Stress
HIV-1
HIV-2
Opportunistic Infections
Helper-Inducer T-Lymphocytes
Reactive Oxygen Species
HIV
Lymphocytes
Therapeutics
Infection
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Zhang, Z., Inserra, P., Liang, B., & Watson, R. R. (2017). Antioxidants and AIDS. In Nutrients and Foods in Aids (pp. 179-192). CRC Press. https://doi.org/10.1201/9780203745250

Antioxidants and AIDS. / Zhang, Zhen; Inserra, Paula; Liang, Bailin; Watson, Ronald R.

Nutrients and Foods in Aids. CRC Press, 2017. p. 179-192.

Research output: Chapter in Book/Report/Conference proceedingChapter

Zhang, Z, Inserra, P, Liang, B & Watson, RR 2017, Antioxidants and AIDS. in Nutrients and Foods in Aids. CRC Press, pp. 179-192. https://doi.org/10.1201/9780203745250
Zhang Z, Inserra P, Liang B, Watson RR. Antioxidants and AIDS. In Nutrients and Foods in Aids. CRC Press. 2017. p. 179-192 https://doi.org/10.1201/9780203745250
Zhang, Zhen ; Inserra, Paula ; Liang, Bailin ; Watson, Ronald R. / Antioxidants and AIDS. Nutrients and Foods in Aids. CRC Press, 2017. pp. 179-192
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