Antitumor activity of Bursera schlechtendalii (Burseraceae): Isolation and structure determination of two new lignans

P. B. McDoniel, J. R. Cole

Research output: Contribution to journalArticle

76 Scopus citations

Abstract

Bursera schlechtendalii (Burseraceae) has shown antitumor activity against the 9KB (adenocarcinoma of nasal pharynx) test system. Two new lignans isolated from the biologically active plant fraction were identified as (—)‐trans‐2‐(3″,4″,5″‐trimethoxy‐benzyl)‐3‐(3′,4′‐methylenedioxybenzyl)butyrolactone and (—)‐trans ‐ 2 ‐ (3″,4″ ‐ dimethoxybenzyl) ‐ 3 ‐ (3′,4′ ‐ methylenedioxybenzyl)butyrolactone. In addition, the triterpene α‐amyrin was isolated from the active fraction.

Original languageEnglish (US)
Pages (from-to)1992-1994
Number of pages3
JournalJournal of pharmaceutical sciences
Volume61
Issue number12
DOIs
StatePublished - Dec 1972

Keywords

  • Antitumor activity—isolation and structure determination of two lignans from Bursera schlechtendalii
  • Bursera schlechtendalii (Burseraceae)—isolation and structure determination of two new lignans
  • Lignans—isolated from Bursera schlechtendalii, structure determination
  • α‐Amyrin—isolated from Bursera schlechtendalii

ASJC Scopus subject areas

  • Pharmaceutical Science

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