Antitumor agents from Jatropha macrorhiza (Euphorbiaceae). III

Acetylaleuritolic acid

S. J. Torrance, R. M. Wiedhopf, Jack R Cole

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The triterpene acetylaleuritolic acid was isolated from Jatropha macrorhiza (Euphorbiaceae) and showed tumor-inhibitory properties toward the P-388 lymphocytic leukemia test system. The compound was identified by means of IR, PMR, and mass spectrometry and by its transformation into the known methylacetyloleanolate.

Original languageEnglish (US)
Pages (from-to)1348-1349
Number of pages2
JournalJournal of Pharmaceutical Sciences
Volume66
Issue number9
StatePublished - 1977

Fingerprint

Jatropha
Euphorbiaceae
Lymphoid Leukemia
Triterpenes
Antineoplastic Agents
Mass spectrometry
Tumors
Mass Spectrometry
Neoplasms
acetylaleuritolic acid

ASJC Scopus subject areas

  • Molecular Medicine
  • Chemistry(all)
  • Organic Chemistry
  • Drug Discovery
  • Pharmaceutical Science
  • Pharmacology

Cite this

Antitumor agents from Jatropha macrorhiza (Euphorbiaceae). III : Acetylaleuritolic acid. / Torrance, S. J.; Wiedhopf, R. M.; Cole, Jack R.

In: Journal of Pharmaceutical Sciences, Vol. 66, No. 9, 1977, p. 1348-1349.

Research output: Contribution to journalArticle

@article{5f3d47475fa74e4d86d27134a3b294ce,
title = "Antitumor agents from Jatropha macrorhiza (Euphorbiaceae). III: Acetylaleuritolic acid",
abstract = "The triterpene acetylaleuritolic acid was isolated from Jatropha macrorhiza (Euphorbiaceae) and showed tumor-inhibitory properties toward the P-388 lymphocytic leukemia test system. The compound was identified by means of IR, PMR, and mass spectrometry and by its transformation into the known methylacetyloleanolate.",
author = "Torrance, {S. J.} and Wiedhopf, {R. M.} and Cole, {Jack R}",
year = "1977",
language = "English (US)",
volume = "66",
pages = "1348--1349",
journal = "Journal of Pharmaceutical Sciences",
issn = "0022-3549",
publisher = "John Wiley and Sons Inc.",
number = "9",

}

TY - JOUR

T1 - Antitumor agents from Jatropha macrorhiza (Euphorbiaceae). III

T2 - Acetylaleuritolic acid

AU - Torrance, S. J.

AU - Wiedhopf, R. M.

AU - Cole, Jack R

PY - 1977

Y1 - 1977

N2 - The triterpene acetylaleuritolic acid was isolated from Jatropha macrorhiza (Euphorbiaceae) and showed tumor-inhibitory properties toward the P-388 lymphocytic leukemia test system. The compound was identified by means of IR, PMR, and mass spectrometry and by its transformation into the known methylacetyloleanolate.

AB - The triterpene acetylaleuritolic acid was isolated from Jatropha macrorhiza (Euphorbiaceae) and showed tumor-inhibitory properties toward the P-388 lymphocytic leukemia test system. The compound was identified by means of IR, PMR, and mass spectrometry and by its transformation into the known methylacetyloleanolate.

UR - http://www.scopus.com/inward/record.url?scp=0017738523&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017738523&partnerID=8YFLogxK

M3 - Article

VL - 66

SP - 1348

EP - 1349

JO - Journal of Pharmaceutical Sciences

JF - Journal of Pharmaceutical Sciences

SN - 0022-3549

IS - 9

ER -