Apakaochtodenes A and B: Two tetrahalogenated monoterpenes from the red marine alga Portieria hornemannii

A. A.Leslie Gunatilaka, Valerie J. Paul, Peter U. Park, Melany P. Puglisi, Aaron D. Gitler, Drake S. Eggleston, R. Curtis Haltiwanger, David G.I. Kingston

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

The structure of apakaochtodene A, the minor isomer of two tetrahalogenated ochtodene monoterpenes, isolated from the red marine alga Portieria hornemannii (Lyngbye) Silva has been identified as 6(S(*))bromo- 1,4(S(*)),8(R(*))-trichloro-2(Z)-ochtodene (1) by NMR spectral and X-ray crystallographic analysis. Its geometrical isomer, apakaochtodene B (2), which could not be separated from I and thus characterized as a 95:5 mixture of 2:1 had 1H and 13C NMR spectral characteristics similar to previously known ochtodene (3) and the related tetrahalogenated monoterpene 4.

Original languageEnglish (US)
Pages (from-to)1376-1378
Number of pages3
JournalJournal Of Natural Products
Volume62
Issue number10
DOIs
StatePublished - Oct 1 1999

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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    Gunatilaka, A. A. L., Paul, V. J., Park, P. U., Puglisi, M. P., Gitler, A. D., Eggleston, D. S., Haltiwanger, R. C., & Kingston, D. G. I. (1999). Apakaochtodenes A and B: Two tetrahalogenated monoterpenes from the red marine alga Portieria hornemannii. Journal Of Natural Products, 62(10), 1376-1378. https://doi.org/10.1021/np9901128