Aquaporins in Desert rodent Physiology

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Desert rodents face a sizeable challenge in maintaining salt and water homeostasis due to their life in an arid environment. A number of their organ systems exhibit functional characteristics that limit water loss above that which occurs in non-desert species under similar conditions. These systems include renal, pulmonary, gastrointestinal, nasal, and skin epithelia. The desert rodent kidney preserves body water by producing a highly concentrated urine that reaches a maximum osmolality nearly three times that of the common laboratory rat. The precise mechanism by which urine is concentrated in any mammal is unknown. Insights into the process may be more apparent in species that produce highly concentrated urine. Aquaporin water channels play a fundamental role in water transport in several desert rodent organ systems. The role of aquaporins in facilitating highly effective water preservation in desert rodents is only beginning to be explored. The organ systems of desert rodents and their associated AQPs are described.

Original languageEnglish (US)
Pages (from-to)120-128
Number of pages9
JournalBiological Bulletin
Volume229
Issue number1
StatePublished - Aug 1 2015

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Aquaporins
aquaporins
deserts
Rodentia
rodents
physiology
urine
Water
Urine
water
kidneys
Kidney
Nasal Mucosa
Body Water
dry environmental conditions
osmolality
skin (animal)
Osmolar Concentration
functional properties
body water

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

Aquaporins in Desert rodent Physiology. / Pannabecker, Thomas L.

In: Biological Bulletin, Vol. 229, No. 1, 01.08.2015, p. 120-128.

Research output: Contribution to journalArticle

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