Arabidopsis AUX1 gene: A permease-like regulator of root gravitropism

Malcolm J. Bennett, Alan Marchant, Haydn G. Green, Sean T. May, Sally P. Ward, Paul A. Millner, Amanda R. Walker, Burkhard Schulz, Kenneth A. Feldmann

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Abstract

The plant hormone auxin regulates various developmental processes including root formation, vascular development, and gravitropism. Mutations within the AUX1 gene confer an auxin-resistant root growth phenotype and abolish root gravitropic curvature. Polypeptide sequence similarity to amino acid permeases suggests that AUX1 mediates the transport of an amino acid- like signaling molecule. Indole-3-acetic acid, the major form of auxin in higher plants, is structurally similar to tryptophan and is a likely substrate for the AUX1 gene product. The cloned AUX1 gene can restore the auxin-responsiveness of transgenic aux1 roots. Spatially, AUX1 is expressed in root apical tissues that regulate root gravitropic curvature.

Original languageEnglish (US)
Pages (from-to)948-950
Number of pages3
JournalScience
Volume273
Issue number5277
DOIs
StatePublished - Aug 16 1996

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    Bennett, M. J., Marchant, A., Green, H. G., May, S. T., Ward, S. P., Millner, P. A., Walker, A. R., Schulz, B., & Feldmann, K. A. (1996). Arabidopsis AUX1 gene: A permease-like regulator of root gravitropism. Science, 273(5277), 948-950. https://doi.org/10.1126/science.273.5277.948