Arabidopsis AUX1 gene: A permease-like regulator of root gravitropism

Malcolm J. Bennett, Alan Marchant, Haydn G. Green, Sean T. May, Sally P. Ward, Paul A. Millner, Amanda R. Walker, Burkhard Schulz, Kenneth A Feldmann

Research output: Contribution to journalArticle

672 Citations (Scopus)

Abstract

The plant hormone auxin regulates various developmental processes including root formation, vascular development, and gravitropism. Mutations within the AUX1 gene confer an auxin-resistant root growth phenotype and abolish root gravitropic curvature. Polypeptide sequence similarity to amino acid permeases suggests that AUX1 mediates the transport of an amino acid- like signaling molecule. Indole-3-acetic acid, the major form of auxin in higher plants, is structurally similar to tryptophan and is a likely substrate for the AUX1 gene product. The cloned AUX1 gene can restore the auxin-responsiveness of transgenic aux1 roots. Spatially, AUX1 is expressed in root apical tissues that regulate root gravitropic curvature.

Original languageEnglish (US)
Pages (from-to)948-950
Number of pages3
JournalScience
Volume273
Issue number5277
StatePublished - Aug 16 1996

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Gravitropism
Indoleacetic Acids
Membrane Transport Proteins
Arabidopsis
Genes
Amino Acid Transport Systems
Plant Growth Regulators
Tryptophan
Blood Vessels
Phenotype
Amino Acids
Peptides
Mutation
Growth

ASJC Scopus subject areas

  • General

Cite this

Bennett, M. J., Marchant, A., Green, H. G., May, S. T., Ward, S. P., Millner, P. A., ... Feldmann, K. A. (1996). Arabidopsis AUX1 gene: A permease-like regulator of root gravitropism. Science, 273(5277), 948-950.

Arabidopsis AUX1 gene : A permease-like regulator of root gravitropism. / Bennett, Malcolm J.; Marchant, Alan; Green, Haydn G.; May, Sean T.; Ward, Sally P.; Millner, Paul A.; Walker, Amanda R.; Schulz, Burkhard; Feldmann, Kenneth A.

In: Science, Vol. 273, No. 5277, 16.08.1996, p. 948-950.

Research output: Contribution to journalArticle

Bennett, MJ, Marchant, A, Green, HG, May, ST, Ward, SP, Millner, PA, Walker, AR, Schulz, B & Feldmann, KA 1996, 'Arabidopsis AUX1 gene: A permease-like regulator of root gravitropism', Science, vol. 273, no. 5277, pp. 948-950.
Bennett MJ, Marchant A, Green HG, May ST, Ward SP, Millner PA et al. Arabidopsis AUX1 gene: A permease-like regulator of root gravitropism. Science. 1996 Aug 16;273(5277):948-950.
Bennett, Malcolm J. ; Marchant, Alan ; Green, Haydn G. ; May, Sean T. ; Ward, Sally P. ; Millner, Paul A. ; Walker, Amanda R. ; Schulz, Burkhard ; Feldmann, Kenneth A. / Arabidopsis AUX1 gene : A permease-like regulator of root gravitropism. In: Science. 1996 ; Vol. 273, No. 5277. pp. 948-950.
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