Arginase: Marker, effector, or candidate gene for asthma?

Research output: Contribution to journalArticle

Abstract

Microarray analysis of the expression profiles of lung tissue in two murine models of asthma revealed high levels of arginase I and arginase II activity, in association with IL-4 and IL-13 overexpression (see the related article beginning on page 1863), suggesting that arginine pathways are critical in the pathogenesis of asthma.

Original languageEnglish (US)
Pages (from-to)1815-1817
Number of pages3
JournalJournal of Clinical Investigation
Volume111
Issue number12
DOIs
StatePublished - Jun 2003

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Arginase
Asthma
Critical Pathways
Interleukin-13
Microarray Analysis
Interleukin-4
Genes
Arginine
Lung

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Arginase : Marker, effector, or candidate gene for asthma? / Vercelli, Donata.

In: Journal of Clinical Investigation, Vol. 111, No. 12, 06.2003, p. 1815-1817.

Research output: Contribution to journalArticle

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abstract = "Microarray analysis of the expression profiles of lung tissue in two murine models of asthma revealed high levels of arginase I and arginase II activity, in association with IL-4 and IL-13 overexpression (see the related article beginning on page 1863), suggesting that arginine pathways are critical in the pathogenesis of asthma.",
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