Ascorbic acid absorption in man: influence of divided dose and food

Susanna Yung, Michael Mayersohn, J. Barry Robinson

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The urinary recovery of ascorbic acid (AA) was examined in 3 subjects when the vitamin was given as a single 1 g dose in solution (control), as divided doses in solution (0.125 g every 15 min. for 8 doses) and as a 1 g solution after eating a meal high in fat content. The divided dose and after-meal treatments produced a significant increase in AA absorption compared to the corresponding control experiment, 72% and 69% increase, respectively. Absorption appears to be delayed and prolonged under the latter conditions. These results are consistent with the suggestion that the vitamin is absorbed by a specialized process at sites high in the small intestine.

Original languageEnglish (US)
Pages (from-to)2505-2511
Number of pages7
JournalLife Sciences
Volume28
Issue number22
DOIs
StatePublished - Jun 1 1981

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Ascorbic Acid
Vitamins
Food
Meals
Small Intestine
Eating
Fats
Recovery
Experiments
Therapeutics

ASJC Scopus subject areas

  • Pharmacology

Cite this

Ascorbic acid absorption in man : influence of divided dose and food. / Yung, Susanna; Mayersohn, Michael; Robinson, J. Barry.

In: Life Sciences, Vol. 28, No. 22, 01.06.1981, p. 2505-2511.

Research output: Contribution to journalArticle

Yung, Susanna ; Mayersohn, Michael ; Robinson, J. Barry. / Ascorbic acid absorption in man : influence of divided dose and food. In: Life Sciences. 1981 ; Vol. 28, No. 22. pp. 2505-2511.
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