Ascorbic acid absorption in man - pharmacokinetic implications

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Several early literature reports have suggested the possible existence of a non-passive, saturable process for ascorbic acid absorption in man. The recent work of several investigators confirms the existence of such a mechanism. Based upon an analysis of the data provided by these investigators values of Vmax and Km have been calculated using the equations of saturable absorption kinetics. A method of oral dosing is suggested which should maximize the total amount of vitamin absorbed.

Original languageEnglish (US)
Pages (from-to)140-142
Number of pages3
JournalEuropean Journal of Pharmacology
Volume19
Issue number1
DOIs
StatePublished - 1972
Externally publishedYes

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Ascorbic Acid
Pharmacokinetics
Research Personnel
Vitamins

Keywords

  • Ascorbic acid absorption
  • Saturable absorption

ASJC Scopus subject areas

  • Cellular and Molecular Neuroscience
  • Pharmacology

Cite this

Ascorbic acid absorption in man - pharmacokinetic implications. / Mayersohn, Michael.

In: European Journal of Pharmacology, Vol. 19, No. 1, 1972, p. 140-142.

Research output: Contribution to journalArticle

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