Asperpyrone D and other metabolites of the plant-associated fungal strain Aspergillus tubingensis

Jixun Zhan, G. M Kamal B Gunaherath, E. M Kithsiri Wijeratne, Leslie Gunatilaka

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Bioactivity-guided fractionation of a cytotoxic extract of Aspergillus tubingensis, a fungal strain occurring in the rhizosphere of the Sonoran desert plant, Fallugia paradoxa, afforded a dimeric naphtho-γ-pyrone asperpyrone D, nine known naphtho-γ-pyrones, funalenone, and the cytotoxic cyclic penta-peptide, malformin A1.

Original languageEnglish (US)
Pages (from-to)368-372
Number of pages5
JournalPhytochemistry
Volume68
Issue number3
DOIs
StatePublished - Feb 2007

Fingerprint

Aspergillus tubingensis
Pyrones
pyrones
Aspergillus
Metabolites
metabolites
Sonoran Desert
xerophytes
Pentas
Cyclic Peptides
Rubiaceae
Rhizosphere
Fractionation
Bioactivity
fractionation
rhizosphere
peptides
extracts
asperpyrone D

Keywords

  • Aspergillus tubingensis
  • Asperpyrone D
  • Cytotoxic activity
  • Fallugia paradoxa
  • Malformin A
  • Naphthopyrones
  • Rhizosphere fungus
  • Secondary metabolites

ASJC Scopus subject areas

  • Plant Science
  • Biochemistry
  • Molecular Biology
  • Organic Chemistry
  • Drug Discovery

Cite this

Asperpyrone D and other metabolites of the plant-associated fungal strain Aspergillus tubingensis. / Zhan, Jixun; Gunaherath, G. M Kamal B; Wijeratne, E. M Kithsiri; Gunatilaka, Leslie.

In: Phytochemistry, Vol. 68, No. 3, 02.2007, p. 368-372.

Research output: Contribution to journalArticle

Zhan, Jixun ; Gunaherath, G. M Kamal B ; Wijeratne, E. M Kithsiri ; Gunatilaka, Leslie. / Asperpyrone D and other metabolites of the plant-associated fungal strain Aspergillus tubingensis. In: Phytochemistry. 2007 ; Vol. 68, No. 3. pp. 368-372.
@article{160f85266b924c398056a302fb884f11,
title = "Asperpyrone D and other metabolites of the plant-associated fungal strain Aspergillus tubingensis",
abstract = "Bioactivity-guided fractionation of a cytotoxic extract of Aspergillus tubingensis, a fungal strain occurring in the rhizosphere of the Sonoran desert plant, Fallugia paradoxa, afforded a dimeric naphtho-γ-pyrone asperpyrone D, nine known naphtho-γ-pyrones, funalenone, and the cytotoxic cyclic penta-peptide, malformin A1.",
keywords = "Aspergillus tubingensis, Asperpyrone D, Cytotoxic activity, Fallugia paradoxa, Malformin A, Naphthopyrones, Rhizosphere fungus, Secondary metabolites",
author = "Jixun Zhan and Gunaherath, {G. M Kamal B} and Wijeratne, {E. M Kithsiri} and Leslie Gunatilaka",
year = "2007",
month = "2",
doi = "10.1016/j.phytochem.2006.09.038",
language = "English (US)",
volume = "68",
pages = "368--372",
journal = "Phytochemistry",
issn = "0031-9422",
publisher = "Elsevier Limited",
number = "3",

}

TY - JOUR

T1 - Asperpyrone D and other metabolites of the plant-associated fungal strain Aspergillus tubingensis

AU - Zhan, Jixun

AU - Gunaherath, G. M Kamal B

AU - Wijeratne, E. M Kithsiri

AU - Gunatilaka, Leslie

PY - 2007/2

Y1 - 2007/2

N2 - Bioactivity-guided fractionation of a cytotoxic extract of Aspergillus tubingensis, a fungal strain occurring in the rhizosphere of the Sonoran desert plant, Fallugia paradoxa, afforded a dimeric naphtho-γ-pyrone asperpyrone D, nine known naphtho-γ-pyrones, funalenone, and the cytotoxic cyclic penta-peptide, malformin A1.

AB - Bioactivity-guided fractionation of a cytotoxic extract of Aspergillus tubingensis, a fungal strain occurring in the rhizosphere of the Sonoran desert plant, Fallugia paradoxa, afforded a dimeric naphtho-γ-pyrone asperpyrone D, nine known naphtho-γ-pyrones, funalenone, and the cytotoxic cyclic penta-peptide, malformin A1.

KW - Aspergillus tubingensis

KW - Asperpyrone D

KW - Cytotoxic activity

KW - Fallugia paradoxa

KW - Malformin A

KW - Naphthopyrones

KW - Rhizosphere fungus

KW - Secondary metabolites

UR - http://www.scopus.com/inward/record.url?scp=33846232680&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846232680&partnerID=8YFLogxK

U2 - 10.1016/j.phytochem.2006.09.038

DO - 10.1016/j.phytochem.2006.09.038

M3 - Article

C2 - 17150233

AN - SCOPUS:33846232680

VL - 68

SP - 368

EP - 372

JO - Phytochemistry

JF - Phytochemistry

SN - 0031-9422

IS - 3

ER -