Abstract
Patients with Coloboma, Heart defect, choanal Atresia, Retarded development, Genitorenal and Ear abnormalities (CHARGE) syndrome have been reported to be at high risk for aspiration and swallowing difficulties. Aspiration has been implicated as the most common cause of mortality in these patients. To date, however, aspiration and swallowing disorders in CHARGE patients have not been independently studied. Objective: To determine the prevalence of aspiration and swallowing dysfunction in children with CHARGE syndrome. Methods: A retrospective chart review of 30 children with CHARGE syndrome was performed. Results: Eighteen (60%) children had aspiration observed on video swallow study (VSS), flexible endoscopic evaluation of swallowing (FEES), and/or had otherwise unexplained bronchiectasis noted on CT scan of the chest. Twenty-four children (80%) had evidence of abnormal swallowing such as laryngeal penetration, dyscoordination, poor bolus mobility, or pooling of secretions. Conclusion: Aspiration and swallowing dysfunction are common in children with CHARGE syndrome. Formal evaluation of swallowing function should be part of the standard otolaryngologic examination for these patients.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1205-1209 |
| Number of pages | 5 |
| Journal | International Journal of Pediatric Otorhinolaryngology |
| Volume | 69 |
| Issue number | 9 |
| DOIs | |
| State | Published - Sep 2005 |
| Externally published | Yes |
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Keywords
- Aspiration
- CHARGE syndrome
- Laryngomalacia
- Supraglottoplasty
ASJC Scopus subject areas
- Otorhinolaryngology
- Pediatrics, Perinatology, and Child Health
- Pulmonary and Respiratory Medicine
- Surgery
Cite this
Aspiration in children with CHARGE syndrome. / White, David R.; Giambra, Barbara K.; Hopkin, Robert J.; Daines, Cori L; Rutter, Michael J.
In: International Journal of Pediatric Otorhinolaryngology, Vol. 69, No. 9, 09.2005, p. 1205-1209.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Aspiration in children with CHARGE syndrome
AU - White, David R.
AU - Giambra, Barbara K.
AU - Hopkin, Robert J.
AU - Daines, Cori L
AU - Rutter, Michael J.
PY - 2005/9
Y1 - 2005/9
N2 - Patients with Coloboma, Heart defect, choanal Atresia, Retarded development, Genitorenal and Ear abnormalities (CHARGE) syndrome have been reported to be at high risk for aspiration and swallowing difficulties. Aspiration has been implicated as the most common cause of mortality in these patients. To date, however, aspiration and swallowing disorders in CHARGE patients have not been independently studied. Objective: To determine the prevalence of aspiration and swallowing dysfunction in children with CHARGE syndrome. Methods: A retrospective chart review of 30 children with CHARGE syndrome was performed. Results: Eighteen (60%) children had aspiration observed on video swallow study (VSS), flexible endoscopic evaluation of swallowing (FEES), and/or had otherwise unexplained bronchiectasis noted on CT scan of the chest. Twenty-four children (80%) had evidence of abnormal swallowing such as laryngeal penetration, dyscoordination, poor bolus mobility, or pooling of secretions. Conclusion: Aspiration and swallowing dysfunction are common in children with CHARGE syndrome. Formal evaluation of swallowing function should be part of the standard otolaryngologic examination for these patients.
AB - Patients with Coloboma, Heart defect, choanal Atresia, Retarded development, Genitorenal and Ear abnormalities (CHARGE) syndrome have been reported to be at high risk for aspiration and swallowing difficulties. Aspiration has been implicated as the most common cause of mortality in these patients. To date, however, aspiration and swallowing disorders in CHARGE patients have not been independently studied. Objective: To determine the prevalence of aspiration and swallowing dysfunction in children with CHARGE syndrome. Methods: A retrospective chart review of 30 children with CHARGE syndrome was performed. Results: Eighteen (60%) children had aspiration observed on video swallow study (VSS), flexible endoscopic evaluation of swallowing (FEES), and/or had otherwise unexplained bronchiectasis noted on CT scan of the chest. Twenty-four children (80%) had evidence of abnormal swallowing such as laryngeal penetration, dyscoordination, poor bolus mobility, or pooling of secretions. Conclusion: Aspiration and swallowing dysfunction are common in children with CHARGE syndrome. Formal evaluation of swallowing function should be part of the standard otolaryngologic examination for these patients.
KW - Aspiration
KW - CHARGE syndrome
KW - Laryngomalacia
KW - Supraglottoplasty
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UR - http://www.scopus.com/inward/citedby.url?scp=23244444612&partnerID=8YFLogxK
U2 - 10.1016/j.ijporl.2005.03.030
DO - 10.1016/j.ijporl.2005.03.030
M3 - Article
C2 - 15890414
AN - SCOPUS:23244444612
VL - 69
SP - 1205
EP - 1209
JO - International Journal of Pediatric Otorhinolaryngology
JF - International Journal of Pediatric Otorhinolaryngology
SN - 0165-5876
IS - 9
ER -