Assessment of liver fat in an obese patient population using noncontrast CT fat percent index

Ali F. Jon, Ahmad R. Cheema, Atif N. Khan, Vassilios Raptopoulos, Thomas Hauser, Imad Nasser, Francine K. Welty, Andrew Karellas, Melvin E. Clouse

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Objective: To develop a simplified method to quantify liver fat using computed tomography (CT) fat % index (CTFPI) compared to liver spleen method (CTL/S, CTL-S). Methods: Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CTFPI=[(65-patient HU)/65]×100, normal live r=65 HU. Results: There was a strong linear correlation between CTFPI and the standard method of assessing liver fat using CTL/S (r=-0.901), CTL-S (r=-0.911). Hepatic HU and CTFPI were significantly different in the severely obese group compared to other two groups (P<.05). Conclusion: Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.

Original languageEnglish (US)
Pages (from-to)259-264
Number of pages6
JournalClinical Imaging
Volume38
Issue number3
DOIs
StatePublished - May 2014
Externally publishedYes

Keywords

  • Fat percent index
  • Hepatic steatosis assessment
  • Metabolic syndrome
  • NASH
  • Noncontrast CT
  • Obesity

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Jon, A. F., Cheema, A. R., Khan, A. N., Raptopoulos, V., Hauser, T., Nasser, I., Welty, F. K., Karellas, A., & Clouse, M. E. (2014). Assessment of liver fat in an obese patient population using noncontrast CT fat percent index. Clinical Imaging, 38(3), 259-264. https://doi.org/10.1016/j.clinimag.2014.01.005