Assisted ventilation during 'bystander' CPR in a swine acute myocardial infarction model does not improve outcome

Robert A. Berg, Karl B Kern, Ronald W. Hilwig, Gordon A. Ewy

Research output: Contribution to journalArticle

143 Citations (Scopus)

Abstract

Background: Mouth-to-mouth rescue breathing is a barrier to the performance of bystander cardiopulmonary resuscitation (CPR). We evaluated the need for assisted ventilation during simulated single-rescuer bystander CPR in a swine myocardial infarction model of prehospital cardiac arrest. Methods and Results: Steel cylinders were placed in the mid left anterior descending coronary arteries of 43 swine. Two minutes after ventricular fibrillation, animals were randomly assigned to 10 minutes of hand-bag-valve ventilation with 17% oxygen and 4% carbon dioxide plus chest compressions (CC+V), chest compressions only (CC), or no CPR (control group). Standard advanced life support was then provided. Animals successfully resuscitated received 1 hour of intensive care support and were observed for 24 hours. Five of 14 CC animals, 3 of 15 CC+V animals, and 1 of 14 controls survived for 24 hours (CC versus controls, P=.07). Myocardial oxygen delivery and consumption were greater among surviving animals than nonsurvivors but did not differ between CC and CC+V animals. Conclusions: In this acute myocardial infarction model of prehospital single-rescuer bystander CPR, assisted ventilation did not improve outcome.

Original languageEnglish (US)
Pages (from-to)4364-4371
Number of pages8
JournalCirculation
Volume96
Issue number12
StatePublished - 1997

Fingerprint

Cardiopulmonary Resuscitation
Ventilation
Swine
Thorax
Myocardial Infarction
Mouth Breathing
Steel
Ventricular Fibrillation
Critical Care
Heart Arrest
Carbon Dioxide
Oxygen Consumption
Mouth
Coronary Vessels
Hand
Oxygen
Control Groups

Keywords

  • Cardiopulmonary resuscitation
  • Heart arrest
  • Myocardial blood flow
  • Pulmonary ventilation
  • Survival
  • Ventilation
  • Ventricular fibrillation

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Assisted ventilation during 'bystander' CPR in a swine acute myocardial infarction model does not improve outcome. / Berg, Robert A.; Kern, Karl B; Hilwig, Ronald W.; Ewy, Gordon A.

In: Circulation, Vol. 96, No. 12, 1997, p. 4364-4371.

Research output: Contribution to journalArticle

Berg, Robert A. ; Kern, Karl B ; Hilwig, Ronald W. ; Ewy, Gordon A. / Assisted ventilation during 'bystander' CPR in a swine acute myocardial infarction model does not improve outcome. In: Circulation. 1997 ; Vol. 96, No. 12. pp. 4364-4371.
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KW - Cardiopulmonary resuscitation

KW - Heart arrest

KW - Myocardial blood flow

KW - Pulmonary ventilation

KW - Survival

KW - Ventilation

KW - Ventricular fibrillation

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