Asymmetric syntheses of highly hydrophobic chimeric aromatic amino acids: 2-Amino-3,3'-diarylpropionic acids

Jun Lin, Subo Liao, Victor J. Hruby

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Four conformationally constrained, highly hydrophobic, and enantiomerically pure chimeric aromatic amino acids have been asymmetrically synthesized in 7 steps with overall yields of 20-30%.

Original languageEnglish (US)
Pages (from-to)3117-3120
Number of pages4
JournalTetrahedron Letters
Volume39
Issue number20
DOIs
StatePublished - May 14 1998

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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