Asymmetric synthesis of (2R, 3S) and (2S, 3R) precursors of β-methyl-histidine, -phenylalanine and -tyrosine

Guigen Li, Dinesh Pattel, Victor J. Hruby

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

A systematic series of (2S, 3R) and (2R, 3S) precursors to β-methyl-histidine, -phenylalanine and -tyrosine, which are of significant importance in the design of peptide and protein ligands, have been synthesized in high optically purity and yield.

Original languageEnglish (US)
Pages (from-to)2315-2318
Number of pages4
JournalTetrahedron: Asymmetry
Volume4
Issue number11
DOIs
StatePublished - Nov 1993

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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