Asymmetric synthesis of unusual amino acid: Synthesis of four isomers of β-methyl-3-(2'-naphthyl)alanine

Wei Yuan, Victor J. Hruby

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

The synthesis of all four individual isomers of 3-methyl-3-(2'-naphthyl)analine was accomplished using asymmetric conjugate 1,4-addition followed by direct or indirect azidation using an Evans-type chiral auxiliary (4-phenyl-2-oxazolidinone).

Original languageEnglish (US)
Pages (from-to)3853-3856
Number of pages4
JournalTetrahedron Letters
Volume38
Issue number22
DOIs
StatePublished - Jun 2 1997

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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