Asymmetric synthesis of unusual amino acids: An enantioselective synthesis of the four isomers of D- and L-O-Methyl-2′, β-Dimethyltyrosine

Guigen Li, Keith C. Russell, Mark A. Jarosinski, Victor J. Hruby

Research output: Contribution to journalArticle

37 Scopus citations

Abstract

The four individual isomers of D- and L-O-methyl-2′, β-dimethyltyrosines have been synthesized in high optical purity. The evidence for asymmetric induction was cofirmed by the X-ray analysis of one of the key intermediates.

Original languageEnglish (US)
Pages (from-to)2565-2568
Number of pages4
JournalTetrahedron Letters
Volume34
Issue number16
DOIs
StatePublished - Apr 16 1993

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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