Asymmetric synthesis of unusual amino acids

Synthesis of optically pure isomers of β-methylphenylalanine

Ramalinga Dharanipragada, Ernesto Nicolas, Geza Toth, Victor J Hruby

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

All the four individual isomers of β-methylphenylalanine have been synthesized in very high optical purities by utilizing in part the chiral imide enolate bromination methodology of Evans and co-workers.

Original languageEnglish (US)
Pages (from-to)6841-6844
Number of pages4
JournalTetrahedron Letters
Volume30
Issue number49
DOIs
StatePublished - 1989

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Imides
Halogenation
Isomers
Amino Acids

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Asymmetric synthesis of unusual amino acids : Synthesis of optically pure isomers of β-methylphenylalanine. / Dharanipragada, Ramalinga; Nicolas, Ernesto; Toth, Geza; Hruby, Victor J.

In: Tetrahedron Letters, Vol. 30, No. 49, 1989, p. 6841-6844.

Research output: Contribution to journalArticle

Dharanipragada, Ramalinga ; Nicolas, Ernesto ; Toth, Geza ; Hruby, Victor J. / Asymmetric synthesis of unusual amino acids : Synthesis of optically pure isomers of β-methylphenylalanine. In: Tetrahedron Letters. 1989 ; Vol. 30, No. 49. pp. 6841-6844.
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