Attenuation of pharmaceutically active compounds in aqueous solution by UV/CaO2 process: Influencing factors, degradation mechanism and pathways

Ming Zheng, Kevin D. Daniels, Minkyu Park, Alec Brockway Nienhauser, Erica C. Clevenger, Yongmei Li, Shane A Snyder

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

As freshwater sources continue to be influenced by wastewater effluents, there is a dire need to develop advanced water treatment processes capable of treating the wastewater-derived contaminants, especially for pharmaceutically active compounds (PhACs). Ultraviolet light (UV) combined with calcium peroxide (CaO2) as an advanced oxidation process (AOP) to attenuate five widespread PhACs (carbamazepine (CBZ), primidone (PMD), phenobarbital (PBB), thiamphenicol (TAP) and florfenicol (FF)) was investigated in this paper. The degradation of these compounds followed pseudo-first-order kinetics (R2 > 0.96). The optimum CaO2 dosage was 0.1 g L-1 and lower initial contaminants concentration was beneficial to their degradation. The UV/CaO2 treatment of test PhACs was attributed to the combination of UV/H2O2 and UV-base-photolysis (UV/Ca(OH)2), and the degradation mechanism was recognized as both UV direct photolysis and indirect photolysis caused by reactive radicals (•OH, triplet states of dissolved organic matter (3DOM*), and 1O2). Furthermore, the tentative transformation pathways of the five PhACs were proposed based on the detected intermediates and the degradation mechanisms. The final products of inorganic carbon and nitrogen indicate UV/CaO2 treatment can significantly mineralize test PhACs. Also, the CaO2 addition significantly reduced the energy consumption of UV irradiation according to electrical energy per order. The effective removal of CBZ and PMD in a secondary wastewater effluent by UV/CaO2 treatment demonstrates the potential use of this AOP technology in advanced treatment of wastewater-derived PhACs.

Original languageEnglish (US)
Number of pages1
JournalWater research
Volume164
DOIs
StatePublished - Nov 1 2019

Fingerprint

aqueous solution
Degradation
degradation
Photolysis
Wastewater
photolysis
wastewater
Effluents
Impurities
effluent
Ultraviolet Rays
oxidation
Oxidation
pollutant
inorganic carbon
inorganic nitrogen
Peroxides
Water treatment
dissolved organic matter
Biological materials

Keywords

  • Degradation mechanism
  • Pharmaceutically active compounds (PhACs)
  • Reactive radicals
  • UV/CaO(2)
  • Wastewater effluent

ASJC Scopus subject areas

  • Ecological Modeling
  • Water Science and Technology
  • Waste Management and Disposal
  • Pollution

Cite this

Attenuation of pharmaceutically active compounds in aqueous solution by UV/CaO2 process : Influencing factors, degradation mechanism and pathways. / Zheng, Ming; Daniels, Kevin D.; Park, Minkyu; Nienhauser, Alec Brockway; Clevenger, Erica C.; Li, Yongmei; Snyder, Shane A.

In: Water research, Vol. 164, 01.11.2019.

Research output: Contribution to journalArticle

Zheng, Ming ; Daniels, Kevin D. ; Park, Minkyu ; Nienhauser, Alec Brockway ; Clevenger, Erica C. ; Li, Yongmei ; Snyder, Shane A. / Attenuation of pharmaceutically active compounds in aqueous solution by UV/CaO2 process : Influencing factors, degradation mechanism and pathways. In: Water research. 2019 ; Vol. 164.
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