Attractor reliability reveals deterministic structure in neuronal spike trains

P. H.E. Tiesinga, J. M. Fellous, Terrence J. Sejnowski

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

When periodic current is injected into an integrate-and-fire model neuron, the voltage as a function of time converges from different initial conditions to an attractor that produces reproducible sequences of spikes. The attractor reliability is a measure of the stability of spike trains against intrinsic noise and is quantified here as the inverse of the number of distinct spike trains obtained in response to repeated presentations of the same stimulus. High reliability characterizes neurons that can support a spike-time code, unlike neurons with discharges forming a renewal process (such as a Poisson process). These two classes of responses cannot be distinguished using measures based on the spike-time histogram, but they can be identified by the attractor dynamics of spike trains, as shown here using a new method for calculating the attractor reliability. We applied these methods to spike trains obtained from current injection into cortical neurons recorded in vitro. These spike trains did not form a renewal process and had a higher reliability compared to renewal-like processes with the same spike-time histogram.

Original languageEnglish (US)
Pages (from-to)1629-1650
Number of pages22
JournalNeural computation
Volume14
Issue number7
DOIs
StatePublished - Jul 2002
Externally publishedYes

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Cognitive Neuroscience

Fingerprint Dive into the research topics of 'Attractor reliability reveals deterministic structure in neuronal spike trains'. Together they form a unique fingerprint.

Cite this