Atypical Form of Cervicofacial Actinomycosis Involving the Skull Base and Temporal Bone

Adam McCann, Sameer A. Alvi, Jessica Newman, Kiran Kakarala, Hinrich Staecker, Alexander G Chiu, Jennifer A. Villwock

Research output: Contribution to journalArticle

Abstract

Background: Cervicofacial actinomycosis is an uncommon indolent infection caused by Actinomyces spp that typically affects individuals with innate or adaptive immunodeficiencies. Soft tissues of the face and neck are most commonly involved. Actinomyces osteomyelitis is uncommon; involvement of the skull base and temporal bone is exceedingly rare. The authors present a unique case of refractory cervicofacial actinomycosis with development of skull base and temporal bone osteomyelitis in an otherwise healthy individual. Methods: Case report with literature review. Results: A 69-year-old man presented with a soft tissue infection, culture positive for Actinomyces, over the right maxilla. Previous unsuccessful treatment included local debridement and 6 weeks of intravenous ceftriaxone. He was subsequently treated with conservative debridement and a prolonged course of intravenous followed by oral antibiotic. However, he eventually required multiple procedures, including maxillectomy, pterygopalatine fossa debridement, and a radical mastoidectomy to clear his disease. Postoperatively he was gradually transitioned off intravenous antibiotics. Conclusions: Cervicofacial actinomycosis involves soft tissue surrounding the facial skeleton and oral cavity and is typically associated with a history of mucosal trauma, surgery, or immunodeficiency. The patient was appropriately treated but experienced disease progression and escalation of therapy. Although actinomycosis is typically not an aggressive bacterial infection, this case illustrates the need for prompt recognition of persistent disease and earlier surgical intervention in cases of recalcitrant cervicofacial actinomycosis. Chronic actinomycosis has the potential for significant morbidity.

Original languageEnglish (US)
Pages (from-to)152-156
Number of pages5
JournalAnnals of Otology, Rhinology and Laryngology
Volume128
Issue number2
DOIs
StatePublished - Feb 1 2019

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Cervicofacial Actinomycosis
Temporal Bone
Skull Base
Actinomycosis
Debridement
Actinomyces
Osteomyelitis
Pterygopalatine Fossa
Anti-Bacterial Agents
Soft Tissue Infections
Ceftriaxone
Maxilla
Bacterial Infections
Skeleton
Mouth
Disease Progression
Neck
Morbidity
Wounds and Injuries
Therapeutics

Keywords

  • cervicofacial actinomycosis
  • disease progression
  • osteomyelitis
  • skull base
  • temporal bone

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Atypical Form of Cervicofacial Actinomycosis Involving the Skull Base and Temporal Bone. / McCann, Adam; Alvi, Sameer A.; Newman, Jessica; Kakarala, Kiran; Staecker, Hinrich; Chiu, Alexander G; Villwock, Jennifer A.

In: Annals of Otology, Rhinology and Laryngology, Vol. 128, No. 2, 01.02.2019, p. 152-156.

Research output: Contribution to journalArticle

McCann, Adam ; Alvi, Sameer A. ; Newman, Jessica ; Kakarala, Kiran ; Staecker, Hinrich ; Chiu, Alexander G ; Villwock, Jennifer A. / Atypical Form of Cervicofacial Actinomycosis Involving the Skull Base and Temporal Bone. In: Annals of Otology, Rhinology and Laryngology. 2019 ; Vol. 128, No. 2. pp. 152-156.
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