Bacteria in Asthma Pathogenesis

Michael Insel, Monica Kraft

Research output: Contribution to journalReview article

Abstract

The airways are under continuous assault from aerosolized bacteria and oral flora. The bacteria present in the airways and gastrointestinal tract of neonates promote immune maturation and protect against asthma pathogenesis. Later bacterial infections and perturbations to the microbiome can contribute to asthma pathogenesis, persistence, and severity.

Original languageEnglish (US)
Pages (from-to)377-389
Number of pages13
JournalImmunology and Allergy Clinics of North America
Volume39
Issue number3
DOIs
StatePublished - Aug 2019

Keywords

  • Asthma
  • Bacteria
  • Immunology
  • Microbiology

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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