Bacterial/fungal growth in a combined parenteral nutrition solution

J. Mershon, Wallace M Nogami, J. M. Williams, C. Yoder, H. E. Eitzen, J. A. Lemons

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Appropriately mixed, compatible solutions of glucose, amino acids and lipid have recently become available for clinical use. While a single hyperalimentation solution has several advantages over the conventional two-bottle technique, its effect on infusion-related septicemia is unknown. An in vitro, mock infusion system identical to that used in our newborn intensive care unit was set up to assess the relative growth rates of three microorganisms in several parenteral nutrition mixtures. Growth of Staphylococcus epidermis, Escherichia coli and Candida albicans was measured in seven different alimentation solutions, including two combined solutions. Generally, microbial growth was the same or decreased in combined solutions as compared to fat alone although considerably greater than that observed in nonlipid containing solutions. In addition, the ability of these organisms to pass in-line terminal filters of pore size 0.22 and 1.2 μm was assessed.

Original languageEnglish (US)
Pages (from-to)498-502
Number of pages5
JournalJournal of Parenteral and Enteral Nutrition
Volume10
Issue number5
StatePublished - 1986
Externally publishedYes

Fingerprint

Parenteral Nutrition Solutions
parenteral feeding
microbial growth
Growth
Neonatal Intensive Care Units
Parenteral Nutrition
septicemia
lipids
Staphylococcus
Candida albicans
bottles
Epidermis
Sepsis
neonates
Fats
Escherichia coli
microorganisms
Lipids
Amino Acids
Glucose

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Mershon, J., Nogami, W. M., Williams, J. M., Yoder, C., Eitzen, H. E., & Lemons, J. A. (1986). Bacterial/fungal growth in a combined parenteral nutrition solution. Journal of Parenteral and Enteral Nutrition, 10(5), 498-502.

Bacterial/fungal growth in a combined parenteral nutrition solution. / Mershon, J.; Nogami, Wallace M; Williams, J. M.; Yoder, C.; Eitzen, H. E.; Lemons, J. A.

In: Journal of Parenteral and Enteral Nutrition, Vol. 10, No. 5, 1986, p. 498-502.

Research output: Contribution to journalArticle

Mershon, J, Nogami, WM, Williams, JM, Yoder, C, Eitzen, HE & Lemons, JA 1986, 'Bacterial/fungal growth in a combined parenteral nutrition solution', Journal of Parenteral and Enteral Nutrition, vol. 10, no. 5, pp. 498-502.
Mershon, J. ; Nogami, Wallace M ; Williams, J. M. ; Yoder, C. ; Eitzen, H. E. ; Lemons, J. A. / Bacterial/fungal growth in a combined parenteral nutrition solution. In: Journal of Parenteral and Enteral Nutrition. 1986 ; Vol. 10, No. 5. pp. 498-502.
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