Banking of adipose- and cord tissue-derived stem cells: Technical and regulatory issues

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Abstract

Stem cells are found in all multicellular organisms and are defined as cells that can differentiate into specialized mature cells as well as divide to produce more stem cells. Mesenchymal stem cells (MSC) were among the first stem cell types to be utilized for regenerative medicine. Although initially isolated from bone marrow, based on ease and costs of procurement, MSC derived from adipose tissue (AT-MSC) and umbilical cord tissue (CT-MSC) are now preferred stem cell sources for these applications. Both adipose tissues and cord tissue present unique problems for biobanking however, in that these are whole tissues, not cellular suspensions. Although the tissues could be processed to facilitate the biobanking process, by doing so additional regulatory issues arise that must be addressed. This review will discuss the technical issues associated with biobanking of these tissues, as well as regulatory concerns when banking of utilizing MSC derived from these sources in the clinic.

Original languageEnglish (US)
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Pages147-154
Number of pages8
Volume951
DOIs
StatePublished - Nov 1 2016

Publication series

NameAdvances in Experimental Medicine and Biology
Volume951
ISSN (Print)00652598
ISSN (Electronic)22148019

Keywords

  • Adipose tissue
  • Biobanking
  • Cord tissue
  • FDA
  • Regenerative medicine
  • Regulations
  • Stem cells

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'Banking of adipose- and cord tissue-derived stem cells: Technical and regulatory issues'. Together they form a unique fingerprint.

  • Cite this

    Harris, D. T. (2016). Banking of adipose- and cord tissue-derived stem cells: Technical and regulatory issues. In Advances in Experimental Medicine and Biology (Vol. 951, pp. 147-154). (Advances in Experimental Medicine and Biology; Vol. 951). Springer New York LLC. https://doi.org/10.1007/978-3-319-45457-3_12