Biology, genome organization, and evolution of parvoviruses in marine shrimp

Arun K. Dhar, Refugio Robles-Sikisaka, Vanvimon Saksmerprome, Dilip K. Lakshman

Research output: Chapter in Book/Report/Conference proceedingChapter

15 Scopus citations

Abstract

As shrimp aquaculture has evolved from a subsistent farming activity to an economically important global industry, viral diseases have also become a serious threat to the sustainable growth and productivity of this industry. Parvoviruses represent an economically important group of viruses that has greatly affected shrimp aquaculture. In the early 1980s, an outbreak of a shrimp parvovirus, infectious hypodermal and hematopoietic necrosis virus (IHHNV), led to the collapse of penaeid shrimp farming in theAmericas. Since then, considerable progress has been made in characterizing the parvoviruses of shrimp and developing diagnostic methods aimed to preventing the spread of diseases caused by these viruses. To date, four parvoviruses are known that infect shrimp; these include IHHNV, hepatopancreatic parvovirus (HPV), spawner-isolated mortality virus (SMV), and lymphoid organ parvo-like virus. Due to the economic repercussions that IHHNV and HPV outbreaks have caused to shrimp farming over the years, studies have been focused mostly on these two pathogens, while information on SMV and LPV remains limited. IHHNV was the first shrimp virus to be sequenced and the first for which highly sensitive diagnostic methods were developed. IHHNV-resistant lines of shrimp were also developed to mitigate the losses caused by this virus. While the losses due to IHHNV have been largely contained in recent years, reports of HPV-induced mortalities in larval stages in hatchery and losses due to reduced growth have increased.This review presents a comprehensive account of the history and current knowledge on the biology, diagnostics methods, genomic features, mechanisms of evolution, and management strategies of shrimp parvoviruses. We also highlighted areas where research efforts should be focused in order to gain further insight on the mechanisms of parvoviral pathogenicity in shrimp that will help to prevent future losses caused by these viruses.

Original languageEnglish (US)
Title of host publicationAdvances in Virus Research
PublisherAcademic Press Inc.
Pages85-139
Number of pages55
DOIs
StatePublished - 2014
Externally publishedYes

Publication series

NameAdvances in Virus Research
Volume89
ISSN (Print)0065-3527
ISSN (Electronic)1557-8399

Keywords

  • Hepatopancreatic parvovirus
  • Infectious hypodermal and hematopoietic necrosis virus
  • Lymphoidal parvo-like virus
  • Parvovirus
  • Penaeus monodon densovirus
  • Penaeus stylirostris densovirus
  • Shrimp
  • Spawner-isolated mortality virus

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Biology, genome organization, and evolution of parvoviruses in marine shrimp'. Together they form a unique fingerprint.

  • Cite this

    Dhar, A. K., Robles-Sikisaka, R., Saksmerprome, V., & Lakshman, D. K. (2014). Biology, genome organization, and evolution of parvoviruses in marine shrimp. In Advances in Virus Research (pp. 85-139). (Advances in Virus Research; Vol. 89). Academic Press Inc.. https://doi.org/10.1016/B978-0-12-800172-1.00003-3