Biomechanical models of hyphal growth in actinomycetes

Alain Goriely, Michael Tabor

Research output: Contribution to journalArticle

58 Scopus citations

Abstract

The tip growth of filamentary actinomycetes is investigated within the framework of large deformation membrane theory in which the cell wall is represented as a growing elastic membrane with geometry-dependent elastic properties. The model exhibits realistic hyphal shapes and indicates a self-similar tip growth mechanism consistent with that observed in experiments. It also demonstrates a simple mechanism for hyphal swelling and beading that is observed in the presence of a lysing agent.

Original languageEnglish (US)
Pages (from-to)211-218
Number of pages8
JournalJournal of Theoretical Biology
Volume222
Issue number2
DOIs
StatePublished - May 21 2003

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Keywords

  • Bio-elasticity
  • Filamentary micro-organisms
  • Large deformation theory
  • Tip growth

ASJC Scopus subject areas

  • Statistics and Probability
  • Modeling and Simulation
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Agricultural and Biological Sciences(all)
  • Applied Mathematics

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