The use of a field-deployable biosensor device in a networked system in a real animal/human environment is important to monitor the spread of dangerous viral pathogens. Surrogate molecules have been used to perform experimental monitoring and/or computational fluid dynamics (CFD) studies, including smoke (for particulate movement) and CO2 (to simulate respiration). The current standard for detecting both porcine reproductive and respiratory syndrome (PRRSV) and influenza A is reverse transcription polymerase chain reaction (RT-PCR), which may take up to four hours to perform, including sample pre-processing, reverse transcription, thermocycling, and gel imaging for product identification. A lab-on-a-chip (LOC) is used to monitor airborne pathogens and enable to perform sample handling, mixing, dilution, electrophoresis, staining, and detection in a single integrated system. The three-dimensional CFD model would serve as a good model for monitoring the spread of many other viral pathogens within animal and human environments.
|Original language||English (US)|
|Number of pages||3|
|Journal||Resource: Engineering and Technology for Sustainable World|
|State||Published - Sep 1 2010|
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)