Biosensor detection CS of an airborne mystery disease

Jeong Yeol Yoon, Hyuck Jin Kwon

Research output: Contribution to journalArticle

Abstract

The use of a field-deployable biosensor device in a networked system in a real animal/human environment is important to monitor the spread of dangerous viral pathogens. Surrogate molecules have been used to perform experimental monitoring and/or computational fluid dynamics (CFD) studies, including smoke (for particulate movement) and CO2 (to simulate respiration). The current standard for detecting both porcine reproductive and respiratory syndrome (PRRSV) and influenza A is reverse transcription polymerase chain reaction (RT-PCR), which may take up to four hours to perform, including sample pre-processing, reverse transcription, thermocycling, and gel imaging for product identification. A lab-on-a-chip (LOC) is used to monitor airborne pathogens and enable to perform sample handling, mixing, dilution, electrophoresis, staining, and detection in a single integrated system. The three-dimensional CFD model would serve as a good model for monitoring the spread of many other viral pathogens within animal and human environments.

Original languageEnglish (US)
Pages (from-to)5-7
Number of pages3
JournalResource: Engineering and Technology for Sustainable World
Volume17
Issue number5
StatePublished - Sep 1 2010

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ASJC Scopus subject areas

  • Biotechnology
  • Agricultural and Biological Sciences(all)
  • Engineering(all)

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