Biosynthesis of terpenes and steroids. Part X. The sterois of some yeast mutants doubly defective in ergosterol biosynthesis

Derek H.R. Barton, A. A. Leslie Gunatilaka, Trevor R. Jarman, David A. Widdowson, Martin Bard, Robin A. Woods

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Abstract

The sterols of six double mutants of Saccharomyces cerevisiae have been isolated and characterised, and the sterol distribution has been related to the biosynthetic pathway from zymosterol to ergosterol. Hitherto unknown ergosta-5,8-dien-3β-ol and cholesta-7,24-dien-3β-ol have been isolated and characterised.

Original languageEnglish (US)
Pages (from-to)88-92
Number of pages5
JournalJournal of the Chemical Society, Perkin Transactions 1
Issue number1
StatePublished - Dec 1 1975
Externally publishedYes

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ASJC Scopus subject areas

  • Chemistry(all)

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