Bleomycin compatibility with selected intravenous medications

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Three separate in vitro admixture experiments were accomplished with bleomycin and other common parenteral medications. Bleomycin was assayed by a radioimmunoassay procedure. Bleomycin was found to be compatible with a majority of drugs including the aminoglycoside antibiotics, the vinca alkaloid antineoplastics, the antimetabolite fluorouracil, several phosphate salt corticosteroids, diphenhydramine and the anticoagulant heparin sulfate. Incompatible admixtures include the acidic cephalosporin and penicillin-derived antibiotics, the antineoplastics, methotrexate, and mitomycin C, the sodium succinate salt of hydrocortisone as well as ascorbic acid (vitamin C).

Original languageEnglish (US)
Pages (from-to)121-130
Number of pages10
JournalJournal of Medicine
Volume13
Issue number1-2
StatePublished - 1982

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Bleomycin
Antineoplastic Antimetabolites
Ascorbic Acid
Salts
Vinca Alkaloids
Diphenhydramine
Mitomycin
Aminoglycosides
Cephalosporins
Methotrexate
Fluorouracil
Penicillins
Antineoplastic Agents
Anticoagulants
Sulfates
Radioimmunoassay
Heparin
Adrenal Cortex Hormones
Sodium
Phosphates

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Bleomycin compatibility with selected intravenous medications. / Dorr, Robert T; Peng, Y. M.; Alberts, David S.

In: Journal of Medicine, Vol. 13, No. 1-2, 1982, p. 121-130.

Research output: Contribution to journalArticle

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