Blood group-related antigens as markers of malignant potential and heterogeneity in human carcinomas

John S. Conn, Ronald S. Weinstein

Research output: Contribution to journalArticle

94 Scopus citations

Abstract

The expression of BGR-Ags is often aberrant in human carcinomas. The observation that BGR-Ag expression in human bladder carcinomas correlates with prognosis for patients with these tumors is especially interesting in light of the numerous reports of correlations between cell surface glycosylation and malignant phenotype in experimental animal tumors. Many observations suggest how this relation might be mediated. It seems reasonable to anticipate that the study of the BGR-Ags and their expression in carcinoma may emerge from its current predominantly descriptive phase and become an important part of the investigation of human tumor biology.

Original languageEnglish (US)
Pages (from-to)1089-1106
Number of pages18
JournalHuman pathology
Volume17
Issue number11
DOIs
StatePublished - Nov 1986
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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