Breast cancer recurrence after nipple-sparing mastectomy: One institution's experience

Katherine E. Poruk, Jian Ying, Jeremy R. Chidester, Joshua R. Olson, Cindy B. Matsen, Leigh A Neumayer, Jayant Agarwal

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Background Nipple-sparing mastectomy (NSM) has been increasingly used to treat women with breast cancer who wish to preserve the overlying breast skin, but concern remains regarding tumor recurrence. We report our experience performing NSM for breast cancer treatment and prophylaxis over a 6-year period.

Methods A retrospective chart review on patients undergoing NSM or skin-sparing mastectomy (SSM) from 2005 to 2011 was performed.

Results NSM patients were younger (P <.001), had a lower body mass index (P <.001), and were associated with a family cancer risk (P =.01) but not genetic risk (P =.83). There was no difference in the distance between the tumor and the nipple-areola complex when comparing NSM and SSM (P =.47). There was no significant difference in recurrence (P =.08) or survival (P =.38) when comparing NSM and SSM after controlling for age, stage, and surgery laterality.

Conclusions There was no difference in survival or cancer recurrence for NSM or SSM. NSM does not increase the risk of recurrence or decrease survival.

Original languageEnglish (US)
Pages (from-to)212-217
Number of pages6
JournalAmerican Journal of Surgery
Volume209
Issue number1
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

Fingerprint

Nipples
Mastectomy
Breast Neoplasms
Recurrence
Skin
Survival
Neoplasms
Breast
Body Mass Index

Keywords

  • Breast cancer
  • Cancer recurrence
  • Nipple-areola complex
  • Nipple-sparing mastectomy
  • NSM

ASJC Scopus subject areas

  • Surgery
  • Medicine(all)

Cite this

Breast cancer recurrence after nipple-sparing mastectomy : One institution's experience. / Poruk, Katherine E.; Ying, Jian; Chidester, Jeremy R.; Olson, Joshua R.; Matsen, Cindy B.; Neumayer, Leigh A; Agarwal, Jayant.

In: American Journal of Surgery, Vol. 209, No. 1, 01.01.2015, p. 212-217.

Research output: Contribution to journalArticle

Poruk, Katherine E. ; Ying, Jian ; Chidester, Jeremy R. ; Olson, Joshua R. ; Matsen, Cindy B. ; Neumayer, Leigh A ; Agarwal, Jayant. / Breast cancer recurrence after nipple-sparing mastectomy : One institution's experience. In: American Journal of Surgery. 2015 ; Vol. 209, No. 1. pp. 212-217.
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