Burden of lower respiratory infections in the Eastern Mediterranean Region between 1990 and 2015

findings from the Global Burden of Disease 2015 study

Gbd 2015 Eastern Mediterranean Region Lri Collaborators

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objectives: We used data from the Global Burden of Disease 2015 study (GBD) to calculate the burden of lower respiratory infections (LRIs) in the 22 countries of the Eastern Mediterranean Region (EMR) from 1990 to 2015. Methods: We conducted a systematic analysis of mortality and morbidity data for LRI and its specific etiologic factors, including pneumococcus, Haemophilus influenzae type b, Respiratory syncytial virus, and influenza virus. We used modeling methods to estimate incidence, deaths, and disability-adjusted life-years (DALYs). We calculated burden attributable to known risk factors for LRI. Results: In 2015, LRIs were the fourth-leading cause of DALYs, causing 11,098,243 (95% UI 9,857,095–12,396,566) DALYs and 191,114 (95% UI 170,934–210,705) deaths. The LRI DALY rates were higher than global estimates in 2015. The highest and lowest age-standardized rates of DALYs were observed in Somalia and Lebanon, respectively. Undernutrition in childhood and ambient particulate matter air pollution in the elderly were the main risk factors. Conclusions: Our findings call for public health strategies to reduce the level of risk factors in each age group, especially vulnerable child and elderly populations.

Original languageEnglish (US)
Pages (from-to)1-12
Number of pages12
JournalInternational Journal of Public Health
DOIs
StateAccepted/In press - Aug 3 2017

Fingerprint

Mediterranean Region
Mediterranean region
Quality-Adjusted Life Years
Respiratory Tract Infections
disability
Disease
contagious disease
Somalia
Lebanon
death
Haemophilus influenzae type b
Respiratory Syncytial Viruses
Particulate Matter
Air Pollution
air pollution
Streptococcus pneumoniae
Orthomyxoviridae
Malnutrition
morbidity
age group

Keywords

  • DALY
  • Eastern Mediterranean Region
  • Incidence
  • Lower respiratory infection
  • Mortality

ASJC Scopus subject areas

  • Health(social science)
  • Public Health, Environmental and Occupational Health

Cite this

Burden of lower respiratory infections in the Eastern Mediterranean Region between 1990 and 2015 : findings from the Global Burden of Disease 2015 study. / Gbd 2015 Eastern Mediterranean Region Lri Collaborators.

In: International Journal of Public Health, 03.08.2017, p. 1-12.

Research output: Contribution to journalArticle

@article{a0f71465cc3b480e9d1a224a2f120658,
title = "Burden of lower respiratory infections in the Eastern Mediterranean Region between 1990 and 2015: findings from the Global Burden of Disease 2015 study",
abstract = "Objectives: We used data from the Global Burden of Disease 2015 study (GBD) to calculate the burden of lower respiratory infections (LRIs) in the 22 countries of the Eastern Mediterranean Region (EMR) from 1990 to 2015. Methods: We conducted a systematic analysis of mortality and morbidity data for LRI and its specific etiologic factors, including pneumococcus, Haemophilus influenzae type b, Respiratory syncytial virus, and influenza virus. We used modeling methods to estimate incidence, deaths, and disability-adjusted life-years (DALYs). We calculated burden attributable to known risk factors for LRI. Results: In 2015, LRIs were the fourth-leading cause of DALYs, causing 11,098,243 (95{\%} UI 9,857,095–12,396,566) DALYs and 191,114 (95{\%} UI 170,934–210,705) deaths. The LRI DALY rates were higher than global estimates in 2015. The highest and lowest age-standardized rates of DALYs were observed in Somalia and Lebanon, respectively. Undernutrition in childhood and ambient particulate matter air pollution in the elderly were the main risk factors. Conclusions: Our findings call for public health strategies to reduce the level of risk factors in each age group, especially vulnerable child and elderly populations.",
keywords = "DALY, Eastern Mediterranean Region, Incidence, Lower respiratory infection, Mortality",
author = "{Gbd 2015 Eastern Mediterranean Region Lri Collaborators} and Maziar Moradi-Lakeh and {El Bcheraoui}, Charbel and Raghid Charara and Ibrahim Khalil and Ashkan Afshin and Kassebaum, {Nicholas J.} and Michael Collison and Farah Daoud and Adrienne Chew and Krohn, {Kristopher J.} and Danny Colombara and Rebecca Ehrenkranz and Foreman, {Kyle J.} and Joseph Frostad and Godwin, {William W.} and Michael Kutz and Rao, {Puja C.} and Robert Reiner and Christopher Troeger and Haidong Wang and Abajobir, {Amanuel Alemu} and Abbas, {Kaja M.} and Abera, {Semaw Ferede} and Abu-Raddad, {Laith J.} and Kelemework Adane and Kiadaliri, {Aliasghar Ahmad} and Alireza Ahmadi and Ahmed, {Muktar Beshir} and Ayman Al-Eyadhy and Khurshid Alam and Noore Alam and Deena Alasfoor and Reza Alizadeh-Navaei and Fatma Al-Maskari and Rajaa Al-Raddadi and Ubai Alsharif and Altirkawi, {Khalid A.} and Nahla Anber and Hossein Ansari and Antonio, {Carl Abelardo T.} and Palwasha Anwari and Hamid Asayesh and Asgedom, {Solomon Weldegebreal} and Atey, {Tesfay Mehari} and {Arthur Avokpaho}, {Euripide Frinel G.} and Umar Bacha and Aleksandra Barac and Shahrzad Bazargan-Hejazi and Neeraj Bedi and Oren, {Eyal -}",
year = "2017",
month = "8",
day = "3",
doi = "10.1007/s00038-017-1007-0",
language = "English (US)",
pages = "1--12",
journal = "Sozial- und Praventivmedizin",
issn = "0303-8408",
publisher = "Birkhauser Verlag Basel",

}

TY - JOUR

T1 - Burden of lower respiratory infections in the Eastern Mediterranean Region between 1990 and 2015

T2 - findings from the Global Burden of Disease 2015 study

AU - Gbd 2015 Eastern Mediterranean Region Lri Collaborators

AU - Moradi-Lakeh, Maziar

AU - El Bcheraoui, Charbel

AU - Charara, Raghid

AU - Khalil, Ibrahim

AU - Afshin, Ashkan

AU - Kassebaum, Nicholas J.

AU - Collison, Michael

AU - Daoud, Farah

AU - Chew, Adrienne

AU - Krohn, Kristopher J.

AU - Colombara, Danny

AU - Ehrenkranz, Rebecca

AU - Foreman, Kyle J.

AU - Frostad, Joseph

AU - Godwin, William W.

AU - Kutz, Michael

AU - Rao, Puja C.

AU - Reiner, Robert

AU - Troeger, Christopher

AU - Wang, Haidong

AU - Abajobir, Amanuel Alemu

AU - Abbas, Kaja M.

AU - Abera, Semaw Ferede

AU - Abu-Raddad, Laith J.

AU - Adane, Kelemework

AU - Kiadaliri, Aliasghar Ahmad

AU - Ahmadi, Alireza

AU - Ahmed, Muktar Beshir

AU - Al-Eyadhy, Ayman

AU - Alam, Khurshid

AU - Alam, Noore

AU - Alasfoor, Deena

AU - Alizadeh-Navaei, Reza

AU - Al-Maskari, Fatma

AU - Al-Raddadi, Rajaa

AU - Alsharif, Ubai

AU - Altirkawi, Khalid A.

AU - Anber, Nahla

AU - Ansari, Hossein

AU - Antonio, Carl Abelardo T.

AU - Anwari, Palwasha

AU - Asayesh, Hamid

AU - Asgedom, Solomon Weldegebreal

AU - Atey, Tesfay Mehari

AU - Arthur Avokpaho, Euripide Frinel G.

AU - Bacha, Umar

AU - Barac, Aleksandra

AU - Bazargan-Hejazi, Shahrzad

AU - Bedi, Neeraj

AU - Oren, Eyal -

PY - 2017/8/3

Y1 - 2017/8/3

N2 - Objectives: We used data from the Global Burden of Disease 2015 study (GBD) to calculate the burden of lower respiratory infections (LRIs) in the 22 countries of the Eastern Mediterranean Region (EMR) from 1990 to 2015. Methods: We conducted a systematic analysis of mortality and morbidity data for LRI and its specific etiologic factors, including pneumococcus, Haemophilus influenzae type b, Respiratory syncytial virus, and influenza virus. We used modeling methods to estimate incidence, deaths, and disability-adjusted life-years (DALYs). We calculated burden attributable to known risk factors for LRI. Results: In 2015, LRIs were the fourth-leading cause of DALYs, causing 11,098,243 (95% UI 9,857,095–12,396,566) DALYs and 191,114 (95% UI 170,934–210,705) deaths. The LRI DALY rates were higher than global estimates in 2015. The highest and lowest age-standardized rates of DALYs were observed in Somalia and Lebanon, respectively. Undernutrition in childhood and ambient particulate matter air pollution in the elderly were the main risk factors. Conclusions: Our findings call for public health strategies to reduce the level of risk factors in each age group, especially vulnerable child and elderly populations.

AB - Objectives: We used data from the Global Burden of Disease 2015 study (GBD) to calculate the burden of lower respiratory infections (LRIs) in the 22 countries of the Eastern Mediterranean Region (EMR) from 1990 to 2015. Methods: We conducted a systematic analysis of mortality and morbidity data for LRI and its specific etiologic factors, including pneumococcus, Haemophilus influenzae type b, Respiratory syncytial virus, and influenza virus. We used modeling methods to estimate incidence, deaths, and disability-adjusted life-years (DALYs). We calculated burden attributable to known risk factors for LRI. Results: In 2015, LRIs were the fourth-leading cause of DALYs, causing 11,098,243 (95% UI 9,857,095–12,396,566) DALYs and 191,114 (95% UI 170,934–210,705) deaths. The LRI DALY rates were higher than global estimates in 2015. The highest and lowest age-standardized rates of DALYs were observed in Somalia and Lebanon, respectively. Undernutrition in childhood and ambient particulate matter air pollution in the elderly were the main risk factors. Conclusions: Our findings call for public health strategies to reduce the level of risk factors in each age group, especially vulnerable child and elderly populations.

KW - DALY

KW - Eastern Mediterranean Region

KW - Incidence

KW - Lower respiratory infection

KW - Mortality

UR - http://www.scopus.com/inward/record.url?scp=85026828839&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85026828839&partnerID=8YFLogxK

U2 - 10.1007/s00038-017-1007-0

DO - 10.1007/s00038-017-1007-0

M3 - Article

SP - 1

EP - 12

JO - Sozial- und Praventivmedizin

JF - Sozial- und Praventivmedizin

SN - 0303-8408

ER -