Calcinogenic factor in Solanum malacoxylon: Evidence that it is 1,25-dihydroxyvitamin D3-glycoside

R. H. Wasserman, John D. Henion, Mark R Haussler, Toni A. McCain

Research output: Contribution to journalArticle

76 Citations (Scopus)

Abstract

After glycosidic cleavage of the water-soluble vitamin D-like principle of the calcinogenic plant Solanum malacoxylon, the active lipophilic portion was purified by column chromatography and analyzed by combined gas chromatography and mass spectrometry. It was identified as 1,25-dihydroxyvitamin D3, the active form of vitamin D. Thus this active metabolite of vitamin D exists in the plant world, and its presence probably accounts for pathologic calcification in grazing animals ingesting Solanum malacoxylon.

Original languageEnglish (US)
Pages (from-to)853-855
Number of pages3
JournalScience
Volume194
Issue number4267
StatePublished - 1976

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Solanum
Calcitriol
Glycosides
Vitamin D
Calcinosis
Herbivory
Gas Chromatography-Mass Spectrometry
Chromatography
Water

ASJC Scopus subject areas

  • General

Cite this

Calcinogenic factor in Solanum malacoxylon : Evidence that it is 1,25-dihydroxyvitamin D3-glycoside. / Wasserman, R. H.; Henion, John D.; Haussler, Mark R; McCain, Toni A.

In: Science, Vol. 194, No. 4267, 1976, p. 853-855.

Research output: Contribution to journalArticle

Wasserman, RH, Henion, JD, Haussler, MR & McCain, TA 1976, 'Calcinogenic factor in Solanum malacoxylon: Evidence that it is 1,25-dihydroxyvitamin D3-glycoside', Science, vol. 194, no. 4267, pp. 853-855.
Wasserman, R. H. ; Henion, John D. ; Haussler, Mark R ; McCain, Toni A. / Calcinogenic factor in Solanum malacoxylon : Evidence that it is 1,25-dihydroxyvitamin D3-glycoside. In: Science. 1976 ; Vol. 194, No. 4267. pp. 853-855.
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