Calcium and TRP channels in pulmonary vascular smooth muscle cell proliferation

Judd W. Landsberg, Jason Yuan

Research output: Contribution to journalArticle

84 Citations (Scopus)

Abstract

Ca2+ is a major trigger for pulmonary vasoconstriction and a stimulus for pulmonary vascular smooth muscle cell proliferation. The transient receptor potential cation channels participate in regulating intracellular Ca2+ and thus vascular contractility and cell proliferation. Upregulation of genes encoding these channels is involved in the development of pulmonary hypertension.

Original languageEnglish (US)
Pages (from-to)44-50
Number of pages7
JournalNews in Physiological Sciences
Volume19
Issue number2
DOIs
StatePublished - Apr 2004
Externally publishedYes

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Calcium Channels
Vascular Smooth Muscle
Smooth Muscle Myocytes
Cell Proliferation
Transient Receptor Potential Channels
Lung
Vasoconstriction
Pulmonary Hypertension
Blood Vessels
Up-Regulation
Genes

ASJC Scopus subject areas

  • Physiology

Cite this

Calcium and TRP channels in pulmonary vascular smooth muscle cell proliferation. / Landsberg, Judd W.; Yuan, Jason.

In: News in Physiological Sciences, Vol. 19, No. 2, 04.2004, p. 44-50.

Research output: Contribution to journalArticle

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