Calcium and TRP channels in pulmonary vascular smooth muscle cell proliferation

Judd W. Landsberg, Jason X.J. Yuan

Research output: Contribution to journalReview article

86 Scopus citations

Abstract

Ca2+ is a major trigger for pulmonary vasoconstriction and a stimulus for pulmonary vascular smooth muscle cell proliferation. The transient receptor potential cation channels participate in regulating intracellular Ca2+ and thus vascular contractility and cell proliferation. Upregulation of genes encoding these channels is involved in the development of pulmonary hypertension.

Original languageEnglish (US)
Pages (from-to)44-50
Number of pages7
JournalNews in Physiological Sciences
Volume19
Issue number2
DOIs
StatePublished - Apr 2004

ASJC Scopus subject areas

  • Physiology

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