Can fish oil interfere with chemotherapy?

Research output: Contribution to journalArticle

Abstract

This basic science paper explores the role of the tumor microenvironment in the development of tumor resistance to chemotherapy. Two distinct fatty acid molecules, endogenously produced by cancer cells in response to platinum-based chemotherapy drugs, were found to confer significant tumor chemoresistance. Remarkably, these two fatty acids also were shown to be present in several commercial fish oil products, and, of potential import to clinicians, the oral administration of small amounts of these fish oils induced tumor resistance to cisplatin in a mouse tumor model.

Original languageEnglish (US)
Pages (from-to)121-123
Number of pages3
JournalAlternative Medicine Alert
Volume14
Issue number11
StatePublished - Nov 2011

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Fish Oils
Drug Therapy
Neoplasms
Fatty Acids
Fish Products
Industrial Oils
Tumor Microenvironment
Platinum
Cisplatin
Oral Administration
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Complementary and alternative medicine

Cite this

Can fish oil interfere with chemotherapy? / Horwitz, Randy J.

In: Alternative Medicine Alert, Vol. 14, No. 11, 11.2011, p. 121-123.

Research output: Contribution to journalArticle

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