Can stereotactic fractionated radiation therapy become the standard of care for early stage non-small cell lung carcinoma

Nam P. Nguyen, Linda L Garland, James Welsh, Russell J Hamilton, Deirdre Cohen, Vincent Vinh-Hung

Research output: Contribution to journalArticle

60 Scopus citations


Management of early stages non-small cell lung carcinoma has traditionally been surgery with radiation selected for medically inoperable patients. Recent emergence of stereotactic body radiation therapy allows for delivery of high radiation dose to the tumor while sparing normal lungs. This reviews compares loco-regional control, survival and complications rates between these two treatment modalities. Literature search identifies studies with stereotactic body radiation therapy and surgery for early stages non-small cell lung cancer. Effectiveness and toxicity of these two modalities was assessed. Stereotactic body radiation therapy is associated with minimal morbidity and provides comparable local control and survival in patients with multiple co-morbidities factors. Stereotactic body radiation therapy may become standard of care for operable early stages non-small cell lung cancer.

Original languageEnglish (US)
Pages (from-to)719-727
Number of pages9
JournalCancer Treatment Reviews
Issue number8
Publication statusPublished - Dec 2008



  • Lung cancer
  • Stereotactic lung radiation
  • VATS

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

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