Canadian association of general surgeons and American college of surgeons evidence based reviews in surgery. 21. the risk of surgical site infection is reduced with perioperative oxygen

Karen Brasel, Donna McRitchie, Patch Dellinger, J. S T Barkun, K. Brasel, T. Cogbill, S. Cutter, G. W N Fitzgerald, H. J A Henteleff, A. W. Kirkpatrick, S. Latosinsky, A. Macleon, H. M. MacRae, T. M. Mastracci, R. S. McLeod, Leigh A Neumayer, S. Smith, M. C. Taylor, M. E. McKenzie

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Objective: Does supplemental perioperative oxygen reduce the risk of surgical wound infection after colorectal surgery? Design: Randomized controlled trial. Setting: Multicentre trial that included 14 hospitals in Spain. Patients: 300 patients aged 18-80 years who underwent elective colorectal resection. Patients who had surgery performed laparoscopically or who had minor colon surgery were excluded. Intervention: Patients were randomly allocated to either 30% or 80% fraction of inspired oxygen (FiO2) intraoperatively and for 6 hours postoperatively. Anesthetic treatment and antibiotic administration were standardized. Main Outcome Measure: Surgical site infection (SSI) as defined by the Center for Disease Control. Results: SSI occurred in 35 of 143 patients (24.4%) who were administered 30% Fio2 and in 22 of 148 patients (14.9%) who were administered 80% FiO2 (p = 0.04). The risk of SSI was 39% lower in the 80% group (relative risk [RR], 0.61; 95% confidence interval [CI], 0.38-0.98) versus the 30% FiO2 group. Conclusions: Patients receiving supplemental oxygen have a significant reduction in risk of surgical site infection.

Original languageEnglish (US)
Pages (from-to)214-216
Number of pages3
JournalCanadian Journal of Surgery
Volume50
Issue number3
StatePublished - Jun 2007
Externally publishedYes

Fingerprint

Surgical Wound Infection
Oxygen
Minor Surgical Procedures
Colorectal Surgery
Risk Reduction Behavior
Centers for Disease Control and Prevention (U.S.)
Surgeons
Spain
Multicenter Studies
Anesthetics
Colon
Randomized Controlled Trials
Outcome Assessment (Health Care)
Confidence Intervals
Anti-Bacterial Agents

ASJC Scopus subject areas

  • Surgery

Cite this

Canadian association of general surgeons and American college of surgeons evidence based reviews in surgery. 21. the risk of surgical site infection is reduced with perioperative oxygen. / Brasel, Karen; McRitchie, Donna; Dellinger, Patch; Barkun, J. S T; Brasel, K.; Cogbill, T.; Cutter, S.; Fitzgerald, G. W N; Henteleff, H. J A; Kirkpatrick, A. W.; Latosinsky, S.; Macleon, A.; MacRae, H. M.; Mastracci, T. M.; McLeod, R. S.; Neumayer, Leigh A; Smith, S.; Taylor, M. C.; McKenzie, M. E.

In: Canadian Journal of Surgery, Vol. 50, No. 3, 06.2007, p. 214-216.

Research output: Contribution to journalArticle

Brasel, K, McRitchie, D, Dellinger, P, Barkun, JST, Brasel, K, Cogbill, T, Cutter, S, Fitzgerald, GWN, Henteleff, HJA, Kirkpatrick, AW, Latosinsky, S, Macleon, A, MacRae, HM, Mastracci, TM, McLeod, RS, Neumayer, LA, Smith, S, Taylor, MC & McKenzie, ME 2007, 'Canadian association of general surgeons and American college of surgeons evidence based reviews in surgery. 21. the risk of surgical site infection is reduced with perioperative oxygen', Canadian Journal of Surgery, vol. 50, no. 3, pp. 214-216.
Brasel, Karen ; McRitchie, Donna ; Dellinger, Patch ; Barkun, J. S T ; Brasel, K. ; Cogbill, T. ; Cutter, S. ; Fitzgerald, G. W N ; Henteleff, H. J A ; Kirkpatrick, A. W. ; Latosinsky, S. ; Macleon, A. ; MacRae, H. M. ; Mastracci, T. M. ; McLeod, R. S. ; Neumayer, Leigh A ; Smith, S. ; Taylor, M. C. ; McKenzie, M. E. / Canadian association of general surgeons and American college of surgeons evidence based reviews in surgery. 21. the risk of surgical site infection is reduced with perioperative oxygen. In: Canadian Journal of Surgery. 2007 ; Vol. 50, No. 3. pp. 214-216.
@article{a1b614f0f85641feb2f5ec05331b7921,
title = "Canadian association of general surgeons and American college of surgeons evidence based reviews in surgery. 21. the risk of surgical site infection is reduced with perioperative oxygen",
abstract = "Objective: Does supplemental perioperative oxygen reduce the risk of surgical wound infection after colorectal surgery? Design: Randomized controlled trial. Setting: Multicentre trial that included 14 hospitals in Spain. Patients: 300 patients aged 18-80 years who underwent elective colorectal resection. Patients who had surgery performed laparoscopically or who had minor colon surgery were excluded. Intervention: Patients were randomly allocated to either 30{\%} or 80{\%} fraction of inspired oxygen (FiO2) intraoperatively and for 6 hours postoperatively. Anesthetic treatment and antibiotic administration were standardized. Main Outcome Measure: Surgical site infection (SSI) as defined by the Center for Disease Control. Results: SSI occurred in 35 of 143 patients (24.4{\%}) who were administered 30{\%} Fio2 and in 22 of 148 patients (14.9{\%}) who were administered 80{\%} FiO2 (p = 0.04). The risk of SSI was 39{\%} lower in the 80{\%} group (relative risk [RR], 0.61; 95{\%} confidence interval [CI], 0.38-0.98) versus the 30{\%} FiO2 group. Conclusions: Patients receiving supplemental oxygen have a significant reduction in risk of surgical site infection.",
author = "Karen Brasel and Donna McRitchie and Patch Dellinger and Barkun, {J. S T} and K. Brasel and T. Cogbill and S. Cutter and Fitzgerald, {G. W N} and Henteleff, {H. J A} and Kirkpatrick, {A. W.} and S. Latosinsky and A. Macleon and MacRae, {H. M.} and Mastracci, {T. M.} and McLeod, {R. S.} and Neumayer, {Leigh A} and S. Smith and Taylor, {M. C.} and McKenzie, {M. E.}",
year = "2007",
month = "6",
language = "English (US)",
volume = "50",
pages = "214--216",
journal = "Canadian Journal of Surgery",
issn = "0008-428X",
publisher = "Canadian Medical Association",
number = "3",

}

TY - JOUR

T1 - Canadian association of general surgeons and American college of surgeons evidence based reviews in surgery. 21. the risk of surgical site infection is reduced with perioperative oxygen

AU - Brasel, Karen

AU - McRitchie, Donna

AU - Dellinger, Patch

AU - Barkun, J. S T

AU - Brasel, K.

AU - Cogbill, T.

AU - Cutter, S.

AU - Fitzgerald, G. W N

AU - Henteleff, H. J A

AU - Kirkpatrick, A. W.

AU - Latosinsky, S.

AU - Macleon, A.

AU - MacRae, H. M.

AU - Mastracci, T. M.

AU - McLeod, R. S.

AU - Neumayer, Leigh A

AU - Smith, S.

AU - Taylor, M. C.

AU - McKenzie, M. E.

PY - 2007/6

Y1 - 2007/6

N2 - Objective: Does supplemental perioperative oxygen reduce the risk of surgical wound infection after colorectal surgery? Design: Randomized controlled trial. Setting: Multicentre trial that included 14 hospitals in Spain. Patients: 300 patients aged 18-80 years who underwent elective colorectal resection. Patients who had surgery performed laparoscopically or who had minor colon surgery were excluded. Intervention: Patients were randomly allocated to either 30% or 80% fraction of inspired oxygen (FiO2) intraoperatively and for 6 hours postoperatively. Anesthetic treatment and antibiotic administration were standardized. Main Outcome Measure: Surgical site infection (SSI) as defined by the Center for Disease Control. Results: SSI occurred in 35 of 143 patients (24.4%) who were administered 30% Fio2 and in 22 of 148 patients (14.9%) who were administered 80% FiO2 (p = 0.04). The risk of SSI was 39% lower in the 80% group (relative risk [RR], 0.61; 95% confidence interval [CI], 0.38-0.98) versus the 30% FiO2 group. Conclusions: Patients receiving supplemental oxygen have a significant reduction in risk of surgical site infection.

AB - Objective: Does supplemental perioperative oxygen reduce the risk of surgical wound infection after colorectal surgery? Design: Randomized controlled trial. Setting: Multicentre trial that included 14 hospitals in Spain. Patients: 300 patients aged 18-80 years who underwent elective colorectal resection. Patients who had surgery performed laparoscopically or who had minor colon surgery were excluded. Intervention: Patients were randomly allocated to either 30% or 80% fraction of inspired oxygen (FiO2) intraoperatively and for 6 hours postoperatively. Anesthetic treatment and antibiotic administration were standardized. Main Outcome Measure: Surgical site infection (SSI) as defined by the Center for Disease Control. Results: SSI occurred in 35 of 143 patients (24.4%) who were administered 30% Fio2 and in 22 of 148 patients (14.9%) who were administered 80% FiO2 (p = 0.04). The risk of SSI was 39% lower in the 80% group (relative risk [RR], 0.61; 95% confidence interval [CI], 0.38-0.98) versus the 30% FiO2 group. Conclusions: Patients receiving supplemental oxygen have a significant reduction in risk of surgical site infection.

UR - http://www.scopus.com/inward/record.url?scp=34250880764&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34250880764&partnerID=8YFLogxK

M3 - Article

VL - 50

SP - 214

EP - 216

JO - Canadian Journal of Surgery

JF - Canadian Journal of Surgery

SN - 0008-428X

IS - 3

ER -