Carbohydrate deposits on the surfaces of worn extended-wear soft contact lenses

Stephen A Klotz, R. P. Misra, S. I. Butrus

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Three different commercial extended-wear soft contact lenses worn continuously by patients for at least 28 days were stained with fluorescein isothiocyanate-labeled lectins. These lectins detected the presence of α-linked or β-linked D-mannose, D-glucose, D-galactose, L-fucose, N-acetyl-D-glucosamine, N-acetyl-D-galactosamine, and N-acetyl neuraminic acid (sialic acid) on the surfaces of the contact lenses. These saccharides are bound to other sugars that likely account for an integral part of glycoprotein and/or glycolipid deposits on lens surfaces. These tear deposits may contribute to the chemical spoilage of the lens and, furthermore, may serve as specific receptors for pathogenic microorganisms commonly implicated in extended-wear soft contact lens-associated infectious keratitis.

Original languageEnglish (US)
Pages (from-to)974-977
Number of pages4
JournalArchives of Ophthalmology
Volume105
Issue number7
StatePublished - 1987
Externally publishedYes

Fingerprint

Extended-Wear Contact Lenses
Hydrophilic Contact Lens
Lectins
Lenses
Neuraminic Acids
Carbohydrates
Acetylgalactosamine
Fucose
Acetylglucosamine
Keratitis
Glycolipids
Contact Lenses
N-Acetylneuraminic Acid
Mannose
Fluorescein
Tears
Galactose
Glycoproteins
Glucose

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Carbohydrate deposits on the surfaces of worn extended-wear soft contact lenses. / Klotz, Stephen A; Misra, R. P.; Butrus, S. I.

In: Archives of Ophthalmology, Vol. 105, No. 7, 1987, p. 974-977.

Research output: Contribution to journalArticle

@article{95c0c942f08a48c098a245a6afa8da1b,
title = "Carbohydrate deposits on the surfaces of worn extended-wear soft contact lenses",
abstract = "Three different commercial extended-wear soft contact lenses worn continuously by patients for at least 28 days were stained with fluorescein isothiocyanate-labeled lectins. These lectins detected the presence of α-linked or β-linked D-mannose, D-glucose, D-galactose, L-fucose, N-acetyl-D-glucosamine, N-acetyl-D-galactosamine, and N-acetyl neuraminic acid (sialic acid) on the surfaces of the contact lenses. These saccharides are bound to other sugars that likely account for an integral part of glycoprotein and/or glycolipid deposits on lens surfaces. These tear deposits may contribute to the chemical spoilage of the lens and, furthermore, may serve as specific receptors for pathogenic microorganisms commonly implicated in extended-wear soft contact lens-associated infectious keratitis.",
author = "Klotz, {Stephen A} and Misra, {R. P.} and Butrus, {S. I.}",
year = "1987",
language = "English (US)",
volume = "105",
pages = "974--977",
journal = "JAMA Ophthalmology",
issn = "2168-6165",
publisher = "American Medical Association",
number = "7",

}

TY - JOUR

T1 - Carbohydrate deposits on the surfaces of worn extended-wear soft contact lenses

AU - Klotz, Stephen A

AU - Misra, R. P.

AU - Butrus, S. I.

PY - 1987

Y1 - 1987

N2 - Three different commercial extended-wear soft contact lenses worn continuously by patients for at least 28 days were stained with fluorescein isothiocyanate-labeled lectins. These lectins detected the presence of α-linked or β-linked D-mannose, D-glucose, D-galactose, L-fucose, N-acetyl-D-glucosamine, N-acetyl-D-galactosamine, and N-acetyl neuraminic acid (sialic acid) on the surfaces of the contact lenses. These saccharides are bound to other sugars that likely account for an integral part of glycoprotein and/or glycolipid deposits on lens surfaces. These tear deposits may contribute to the chemical spoilage of the lens and, furthermore, may serve as specific receptors for pathogenic microorganisms commonly implicated in extended-wear soft contact lens-associated infectious keratitis.

AB - Three different commercial extended-wear soft contact lenses worn continuously by patients for at least 28 days were stained with fluorescein isothiocyanate-labeled lectins. These lectins detected the presence of α-linked or β-linked D-mannose, D-glucose, D-galactose, L-fucose, N-acetyl-D-glucosamine, N-acetyl-D-galactosamine, and N-acetyl neuraminic acid (sialic acid) on the surfaces of the contact lenses. These saccharides are bound to other sugars that likely account for an integral part of glycoprotein and/or glycolipid deposits on lens surfaces. These tear deposits may contribute to the chemical spoilage of the lens and, furthermore, may serve as specific receptors for pathogenic microorganisms commonly implicated in extended-wear soft contact lens-associated infectious keratitis.

UR - http://www.scopus.com/inward/record.url?scp=0023235692&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023235692&partnerID=8YFLogxK

M3 - Article

VL - 105

SP - 974

EP - 977

JO - JAMA Ophthalmology

JF - JAMA Ophthalmology

SN - 2168-6165

IS - 7

ER -