Carcass of a Pill: No Cause for Alarm

Martin L. Job, John E. Murphy, Harvey Sacks

Research output: Contribution to journalLetter

5 Scopus citations

Abstract

To the Editor: Procan SR (Parke–Davis) is a newly marketed sustained-release formulation of procainamide designed to maintain therapeutic plasma concentrations for approximately six hours. According to the package insert, the drug is available as 250-mg (green) or 500-mg (yellow) oval, wax-matrix tablets. Recently we have had reports from several patients who claimed to have observed the presence of what appeared to be intact, undissolved tablets in their stools. We asked the patients to retrieve the tablets for analysis. One patient submitted what appeared to be an undissolved 500-mg tablet that still retained a well-formed oval shape and some of its. . . No extract is available for articles shorter than 400 words.

Original languageEnglish (US)
Number of pages1
JournalNew England Journal of Medicine
Volume305
Issue number4
DOIs
StatePublished - Jul 23 1981
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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