Castleman's disease of the urachus

Udo Rudloff, Avrum Jacobson, Nora Morgenstern, Yu Chen, Benjamin R. Lee

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Castleman's disease (angiofollicular lymphoid hyperplasia) is a rare heterogeneous group of lymphoproliferative disorders of uncertain cause. Most cases occur as mediastinal masses, although extrathoracic involvement has been reported. Castleman's disease involving the genitourinary tract, one of the most infrequent organ systems affected, has so far only been described in pararenal and retroperitoneal locations. We describe a patient with an unusual case of unicentric Castleman's disease that was located in a urachal remnant and bore a malignant appearance. The patient initially presented with abdominal pain and underwent laparoscopic radical excision of the urachal mass. Pathologic examination revealed Castleman's disease, hyaline-vascular type, with atypical lymphoid proliferation and follicular dendritic cell dysplasia. No evidence of concomitant lymphoma or sarcoma was found. Two years after surgical removal of the tumor, no recurrence was evident. To our knowledge, this is the first case of Castleman's disease presenting as a urachal tumor.

Original languageEnglish (US)
Pages (from-to)376.e7-376.e10
JournalUrology
Volume64
Issue number2
DOIs
StatePublished - Aug 2004
Externally publishedYes

ASJC Scopus subject areas

  • Urology

Fingerprint Dive into the research topics of 'Castleman's disease of the urachus'. Together they form a unique fingerprint.

Cite this